OBJECTIVE: Cloninger's psychobiological model of temperament has recently raised interest as a risk factor for CHD. However, there are no studies that have examined the associations of Cloninger's temperament traits with atherosclerosis. METHODS: The subjects were 398 men and 657 women (mean age 31.7 years) participating in the Cardiovascular Risk in Young Finns Study. Linear regression analyses were used to examine the cross-sectional associations between temperament traits and preclinical atherosclerosis. Preclinical atherosclerosis was measured with carotid intima-media thickness ultrasound. RESULTS: Higher novelty seeking (NS) and reward dependence (RD) and lower harm avoidance (HA) were associated with preclinical atherosclerosis. In NS and RD, associations remained significant after adjustments for various risk factors. The effect sizes of these associations were comparable to those of traditional risk factors of coronary heart disease, which is a major finding. No association for persistence (P) was found. CONCLUSIONS: The present findings imply that examining a wider range of temperament and personality factors may offer new information that can help in explaining the between-individual variation in atherosclerosis and CHD morbidity.
OBJECTIVE: Cloninger's psychobiological model of temperament has recently raised interest as a risk factor for CHD. However, there are no studies that have examined the associations of Cloninger's temperament traits with atherosclerosis. METHODS: The subjects were 398 men and 657 women (mean age 31.7 years) participating in the Cardiovascular Risk in Young Finns Study. Linear regression analyses were used to examine the cross-sectional associations between temperament traits and preclinical atherosclerosis. Preclinical atherosclerosis was measured with carotid intima-media thickness ultrasound. RESULTS: Higher novelty seeking (NS) and reward dependence (RD) and lower harm avoidance (HA) were associated with preclinical atherosclerosis. In NS and RD, associations remained significant after adjustments for various risk factors. The effect sizes of these associations were comparable to those of traditional risk factors of coronary heart disease, which is a major finding. No association for persistence (P) was found. CONCLUSIONS: The present findings imply that examining a wider range of temperament and personality factors may offer new information that can help in explaining the between-individual variation in atherosclerosis and CHD morbidity.
Authors: Robert S Wilson; Patricia A Boyle; Aron S Buchman; Lei Yu; Steven E Arnold; David A Bennett Journal: Psychosom Med Date: 2011-09-23 Impact factor: 4.312
Authors: Mirka Hintsanen; Sampsa Puttonen; Petrus Järvinen; Laura Pulkki-Råback; Marko Elovainio; Päivi Merjonen; Liisa Keltikangas-Järvinen Journal: Int J Behav Med Date: 2009
Authors: Robert S Wilson; Patricia A Boyle; Steven R Levine; Lei Yu; George M Hoganson; Aron S Buchman; Julie A Schneider; David A Bennett Journal: Neuropsychology Date: 2013-12-23 Impact factor: 3.295
Authors: M Oikonen; M Hintsanen; M Laaksonen; V Mikkilä; M Kähönen; T Lehtimäki; L Pulkki-Råback; J S A Viikari; L Keltikangas-Järvinen; O T Raitakari Journal: Int J Behav Med Date: 2014-06
Authors: Aron S Buchman; Lei Yu; Robert S Wilson; Joshua M Shulman; Patricia A Boyle; David A Bennett Journal: BMC Geriatr Date: 2014-04-23 Impact factor: 3.921
Authors: S K Service; K J H Verweij; J Lahti; E Congdon; J Ekelund; M Hintsanen; K Räikkönen; T Lehtimäki; M Kähönen; E Widen; A Taanila; J Veijola; A C Heath; P A F Madden; G W Montgomery; C Sabatti; M-R Järvelin; A Palotie; O Raitakari; J Viikari; N G Martin; J G Eriksson; L Keltikangas-Järvinen; N R Wray; N B Freimer Journal: Transl Psychiatry Date: 2012-05-15 Impact factor: 6.222