Literature DB >> 1953903

The role of p53 in the normal control of cell proliferation.

J Milner1.   

Abstract

The regulation of cell proliferation involves p53. A mutant allele of p53, p53-Val135, has been found to be temperature-sensitive for function with separable suppressor and promoter effects on cell proliferation. These opposing suppressor and promoter functions of p53 correlate with two alternative, temperature-sensitive conformations of the p53-Val135 polypeptide.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1953903     DOI： 10.1016/0955-0674(91)90153-p

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  14 in total

1.  p53 expression in lymphatic malignancies.

Authors:  Y Soini; P Pääkkö; M Alavaikko; K Vähäkangas
Journal:  J Clin Pathol       Date:  1992-11       Impact factor: 3.411

2.  p53-mediated cell death: relationship to cell cycle control.

Authors:  E Yonish-Rouach; D Grunwald; S Wilder; A Kimchi; E May; J J Lawrence; P May; M Oren
Journal:  Mol Cell Biol       Date:  1993-03       Impact factor: 4.272

Review 3.  Molecular biology of testicular germ cell tumors: current status.

Authors:  B Schmidt; R Ackermann; T Strohmeyer
Journal:  J Mol Med (Berl)       Date:  1995-07       Impact factor: 4.599

4.  p53 accumulation in polynuclear-giant-cells.

Authors:  T Wiethege; B Voss; K M Müller
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064

5.  Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells.

Authors:  M F Kulesz-Martin; B Lisafeld; H Huang; N D Kisiel; L Lee
Journal:  Mol Cell Biol       Date:  1994-03       Impact factor: 4.272

6.  Presence of human papillomavirus DNA and abnormal p53 protein accumulation in lung carcinoma.

Authors:  Y Soini; K Nuorva; D Kamel; R Pöllänen; K Vähäkangas; V P Lehto; P Pääkkö
Journal:  Thorax       Date:  1996-09       Impact factor: 9.139

7.  Low p53 protein expression in salivary gland tumours compared with lung carcinomas.

Authors:  Y Soini; D Kamel; K Nuorva; D P Lane; K Vähäkangas; P Pääkkö
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

8.  Gain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness.

Authors:  M Hsiao; J Low; E Dorn; D Ku; P Pattengale; J Yeargin; M Haas
Journal:  Am J Pathol       Date:  1994-09       Impact factor: 4.307

9.  Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells.

Authors:  A von der Weth; W Deppert
Journal:  J Virol       Date:  1993-02       Impact factor: 5.103

10.  p53 expression in oat and non-oat small cell lung carcinomas: correlations with proliferating cell nuclear antigen.

Authors:  P Korkolopoulou; J Oates; J Crocker; C Edwards
Journal:  J Clin Pathol       Date:  1993-12       Impact factor: 3.411
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.