| Literature DB >> 19538923 |
Abstract
NOD1 and 2 are intracellular sentinels critical to innate immunity. In this issue of Immunity, Bertrand et al. (2009) fill in a gap in the NOD signaling cascade by demonstrating that cIAP1 and 2 function as E3 ubiquitin ligases for the RIP2 signaling molecule.Entities:
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Year: 2009 PMID: 19538923 DOI: 10.1016/j.immuni.2009.06.005
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745