Literature DB >> 19536899

Key concerns about the current state of bladder cancer: a position paper from the Bladder Cancer Think Tank, the Bladder Cancer Advocacy Network, and the Society of Urologic Oncology.

Yair Lotan1, Ashish M Kamat, Michael P Porter, Victoria L Robinson, Neal Shore, Michael Jewett, Paul F Schelhammer, Ralph deVere White, Diane Quale, Cheryl T Lee.   

Abstract

Bladder cancer is the fifth most common cancer in the United States and, on a per capita basis, is the most expensive cancer from diagnosis to death. Unfortunately, National Cancer Institute funding for bladder cancer is quite low when compared with other common malignancies. Limited funding has stifled research opportunities for new and established investigators, ultimately encouraging them to redirect research efforts to other organ sites. Waning interest of scientists has further fueled the cycle of modest funding for bladder cancer. One important consequence of this has been a lack of scientific advancement in the field. Patient advocates have decidedly advanced research efforts in many cancer sites. Breast, prostate, pancreatic, and ovarian cancer advocates have organized highly successful campaigns to lobby the federal government and the medical community to devote increased attention and funding to understudied malignancies and to conduct relevant studies to better understand the therapy, diagnosis, and prevention of these diseases. Bladder cancer survivors have lacked a coordinated advocacy voice until recently. A concerted effort to align bladder cancer advocates, clinicians, and urologic organizations is essential to define the greatest needs in bladder cancer and to develop related solutions. This position paper represents a collaborative discussion to define the most concerning trends and greatest needs in the field of bladder cancer as outlined by the Bladder Cancer Think Tank, the Bladder Cancer Advocacy Network, and the Society of Urologic Oncology. Copyright (c) 2009 American Cancer Society.

Entities:  

Mesh:

Year:  2009        PMID: 19536899     DOI: 10.1002/cncr.24463

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  19 in total

1.  Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies.

Authors:  Haiping Zhou; Hong-ying Huang; Ellen Shapiro; Herbert Lepor; William C Huang; Moosa Mohammadi; Ian Mohr; Moon-shong Tang; Chuanshu Huang; Xue-ru Wu
Journal:  Carcinogenesis       Date:  2012-01-27       Impact factor: 4.944

2.  Introduction: Key issues in bladder cancer management.

Authors:  Wassim Kassouf
Journal:  Can Urol Assoc J       Date:  2009-12       Impact factor: 1.862

3.  Transforming Growth Factor-β Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2-Dependent Bladder Cancer Cell Migration and Invasion.

Authors:  Sounak Gupta; Andrew M Hau; Hikmat A Al-Ahmadie; Jyoti Harwalkar; Aaron C Shoskes; Paul Elson; Jordan R Beach; George S Hussey; William P Schiemann; Thomas T Egelhoff; Philip H Howe; Donna E Hansel
Journal:  Am J Pathol       Date:  2016-03-14       Impact factor: 4.307

4.  Bladder cancer: Lack of progress in bladder cancer--what are the obstacles?

Authors:  Mark S Soloway
Journal:  Nat Rev Urol       Date:  2012-11-20       Impact factor: 14.432

5.  Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas.

Authors:  Feng He; Jonathan Melamed; Moon-Shong Tang; Chuanshu Huang; Xue-Ru Wu
Journal:  Cancer Res       Date:  2015-03-20       Impact factor: 12.701

Review 6.  The Hippo pathway: an emerging role in urologic cancers.

Authors:  Bekir Cinar; Esma Alp; Marwah Al-Mathkour; Ava Boston; Abdulrahman Dwead; Kezhan Khazaw; Alexis Gregory
Journal:  Am J Clin Exp Urol       Date:  2021-08-25

Review 7.  Cell adhesion and urothelial bladder cancer: the role of cadherin switching and related phenomena.

Authors:  Richard T Bryan
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-02-05       Impact factor: 6.237

8.  Point-of-Care Tests for Bladder Cancer: The Influencing Role of Hematuria.

Authors:  Joerg Hennenlotter; Severine Huber; Tilman Todenhöfer; Ursula Kuehs; David Schilling; Stefan Aufderklamm; Georgios Gakis; Christian Schwentner; Arnulf Stenzl
Journal:  Adv Urol       Date:  2011-11-22

9.  Surveillance and treatment of non-muscle-invasive bladder cancer in the USA.

Authors:  Daniel A Barocas; Denise R Globe; Danielle C Colayco; Ahunna Onyenwenyi; Amanda S Bruno; Thomas J Bramley; Rachel J Spear
Journal:  Adv Urol       Date:  2012-05-10

10.  Performance of survivin mRNA as a biomarker for bladder cancer in the prospective study UroScreen.

Authors:  Georg Johnen; Katarzyna Gawrych; Heike Bontrup; Beate Pesch; Dirk Taeger; Séverine Banek; Matthias Kluckert; Harald Wellhäußer; Friedhelm Eberle; Michael Nasterlack; Gabriele Leng; Arnulf Stenzl; Thomas Brüning
Journal:  PLoS One       Date:  2012-04-16       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.