Literature DB >> 19536191

ASMase: the tailor of cytotoxic T cell granule exocytosis.

Christian Bogdan.   

Abstract

Deficiency in acid sphingomyelinase causes lysosomal storage of sphingomyelin, mediates resistance to stress-induced apoptosis and alters susceptibility to certain infections. New work links acid sphingomyelinase to the granule exocytosis of cytotoxic T cells.

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Year:  2009        PMID： 19536191     DOI： 10.1038/ni0709-683

Source DB:  PubMed          Journal:  Nat Immunol        ISSN： 1529-2908            Impact factor:   25.606


  12 in total

1.  Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin.

Authors:  Srikumar M Raja; Baikun Wang; Mandakini Dantuluri; Umesh R Desai; Borries Demeler; Katharina Spiegel; Sunil S Metkar; Christopher J Froelich
Journal:  J Biol Chem       Date:  2002-10-17       Impact factor: 5.157

2.  Pathways of protein secretion in eukaryotes.

Authors:  R B Kelly
Journal:  Science       Date:  1985-10-04       Impact factor: 47.728

3.  Receptor-directed focusing of lymphokine release by helper T cells.

Authors:  W J Poo; L Conrad; C A Janeway
Journal:  Nature       Date:  1988-03-24       Impact factor: 49.962

4.  Severe impairment in early host defense against Listeria monocytogenes in mice deficient in acid sphingomyelinase.

Authors:  Olaf Utermöhlen; Ulrike Karow; Jürgen Löhler; Martin Krönke
Journal:  J Immunol       Date:  2003-03-01       Impact factor: 5.422

Review 5.  The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases.

Authors:  Eric L Smith; Edward H Schuchman
Journal:  FASEB J       Date:  2008-06-20       Impact factor: 5.191

6.  Rapid up-regulation and granule-independent transport of perforin to the immunological synapse define a novel mechanism of antigen-specific CD8+ T cell cytotoxic activity.

Authors:  George Makedonas; Pinaki P Banerjee; Rahul Pandey; Adam R Hersperger; Keri B Sanborn; Gareth A D Hardy; Jordan S Orange; Michael R Betts
Journal:  J Immunol       Date:  2009-05-01       Impact factor: 5.422

7.  Acid sphingomyelinase is required for efficient phago-lysosomal fusion.

Authors:  Michael Schramm; Jasmin Herz; Albert Haas; Martin Krönke; Olaf Utermöhlen
Journal:  Cell Microbiol       Date:  2008-05-13       Impact factor: 3.715

Review 8.  Secretory mechanisms in cell-mediated cytotoxicity.

Authors:  Jane C Stinchcombe; Gillian M Griffiths
Journal:  Annu Rev Cell Dev Biol       Date:  2007       Impact factor: 13.827

9.  Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes.

Authors:  Jasmin Herz; Julian Pardo; Hamid Kashkar; Michael Schramm; Elza Kuzmenkina; Erik Bos; Katja Wiegmann; Reinhard Wallich; Peter J Peters; Stefan Herzig; Elmon Schmelzer; Martin Krönke; Markus M Simon; Olaf Utermöhlen
Journal:  Nat Immunol       Date:  2009-06-14       Impact factor: 25.606

Review 10.  Shouts, whispers and the kiss of death: directional secretion in T cells.

Authors:  Morgan Huse; Emily J Quann; Mark M Davis
Journal:  Nat Immunol       Date:  2008-10       Impact factor: 25.606
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  1 in total

Review 1.  Acid sphingomyelinase in macrophage biology.

Authors:  Jean-Philip Truman; Mohammed M Al Gadban; Kent J Smith; Samar M Hammad
Journal:  Cell Mol Life Sci       Date:  2011-05-02       Impact factor: 9.261
  1 in total

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