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Literature DB >> 19535806

A new target for tumor therapy.

Rakesh K Jain¹.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

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Year: 2009 PMID： 19535806 PMCID： PMC4792114 DOI： 10.1056/NEJMcibr0902054

Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245

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5 in total

Review 1. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy.

Authors: R K Jain
Journal: Nat Med Date: 2001-09 Impact factor: 53.440

2. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

Authors: Frank Winkler; Sergey V Kozin; Ricky T Tong; Sung-Suk Chae; Michael F Booth; Igor Garkavtsev; Lei Xu; Daniel J Hicklin; Dai Fukumura; Emmanuelle di Tomaso; Lance L Munn; Rakesh K Jain
Journal: Cancer Cell Date: 2004-12 Impact factor: 31.743

3. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.

Authors: Massimiliano Mazzone; Daniela Dettori; Rodrigo Leite de Oliveira; Sonja Loges; Thomas Schmidt; Bart Jonckx; Ya-Min Tian; Anthony A Lanahan; Patrick Pollard; Carmen Ruiz de Almodovar; Frederik De Smet; Stefan Vinckier; Julián Aragonés; Koen Debackere; Aernout Luttun; Sabine Wyns; Benedicte Jordan; Alberto Pisacane; Bernard Gallez; Maria Grazia Lampugnani; Elisabetta Dejana; Michael Simons; Peter Ratcliffe; Patrick Maxwell; Peter Carmeliet
Journal: Cell Date: 2009-02-12 Impact factor: 41.582

Review 4. Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.

Authors: Rakesh K Jain
Journal: Nat Rev Cancer Date: 2008-04 Impact factor: 60.716

5. Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.

Authors: Walid S Kamoun; Carsten D Ley; Christian T Farrar; Annique M Duyverman; Johanna Lahdenranta; Delphine A Lacorre; Tracy T Batchelor; Emmanuelle di Tomaso; Dan G Duda; Lance L Munn; Dai Fukumura; A Gregory Sorensen; Rakesh K Jain
Journal: J Clin Oncol Date: 2009-03-30 Impact factor: 44.544

5 in total

24 in total

1. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw.

Authors: Shibani Pati; Nena Matijevic; Marie-Françoise Doursout; Tien Ko; Yanna Cao; Xiyun Deng; Rosemary A Kozar; Elizabeth Hartwell; Jodie Conyers; John B Holcomb
Journal: J Trauma Date: 2010-07

2. Glioblastoma multiforme: Molecular characterization and current treatment strategy (Review).

Authors: Xiang Zhang; Wei Zhang; Wei-Dong Cao; Gang Cheng; Yong-Qiang Zhang
Journal: Exp Ther Med Date: 2011-10-18 Impact factor: 2.447

Review 3. Pulsed Electron Paramagnetic Resonance Imaging: Applications in the Studies of Tumor Physiology.

Authors: Shun Kishimoto; Ken-Ichiro Matsumoto; Keita Saito; Ayano Enomoto; Shingo Matsumoto; James B Mitchell; Nallathamby Devasahayam; Murali C Krishna
Journal: Antioxid Redox Signal Date: 2018-01-09 Impact factor: 8.401

4. Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer.

Authors: Dan G Duda; Christopher G Willett; Marek Ancukiewicz; Emmanuelle di Tomaso; Mira Shah; Brian G Czito; Rex Bentley; Martin Poleski; Gregory Y Lauwers; Madeline Carroll; Douglas Tyler; Christopher Mantyh; Paul Shellito; Jeffrey W Clark; Rakesh K Jain
Journal: Oncologist Date: 2010-05-18

A new target for tumor therapy.

Review 1. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy.

2. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

3. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.

Review 4. Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer.

5. Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.

1. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw.

2. Glioblastoma multiforme: Molecular characterization and current treatment strategy (Review).

Review 3. Pulsed Electron Paramagnetic Resonance Imaging: Applications in the Studies of Tumor Physiology.

4. Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer.

Review 5. Current approaches and recent developments in the management of head and neck paragangliomas.

Review 6. Subcellular Energetics and Metabolism: Potential Therapeutic Applications.

7. Expression and effect of proline hydroxylase domain 2 in retina of diabetic rats.

8. Differential changes in platelet VEGF, Tsp, CXCL12, and CXCL4 in patients with metastatic cancer.

9. Low dose radiation primed iNOS + M1macrophages modulate angiogenic programming of tumor derived endothelium.

10. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles.