Literature DB >> 195342

Three hypolipidemic drugs increase hepatic palmitoyl-coenzyme A oxidation in the rat.

P B Lazarow.   

Abstract

Male rats treated with clofibrate, tibric acid, or Wy-14,643 show an 11- to 18-fold increase in the capacity of their livers to oxidize palmitoyl-coenzyme A. This provides a plausible biochemical mechanism for the action of these hypolipidemic drugs in reducing lipid concentrations in the serum.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 195342     DOI： 10.1126/science.195342

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  36 in total

1.  Turnover of fatty acyl-CoA oxidase in the liver of rats fed on a partially hydrogenated marine oil.

Authors:  S Horie; T Suga
Journal:  Lipids       Date:  1989-10       Impact factor: 1.880

2.  The effect of feeding fish oils, vegetable oils and clofibrate on the ketogenesis from long chain fatty acids in hepatocytes.

Authors:  S Bergseth; E N Christiansen; J Bremer
Journal:  Lipids       Date:  1986-08       Impact factor: 1.880

Review 3.  Peroxisomal disorders: a newly recognised group of genetic diseases.

Authors:  R B Schutgens; H S Heymans; R J Wanders; H van den Bosch; J M Tager
Journal:  Eur J Pediatr       Date:  1986-02       Impact factor: 3.183

4.  Carnitine acyltransferase and acyl-coenzyme A hydrolase activities in human liver. Quantitative analysis of their subcellular localization.

Authors:  M Bronfman; F Leighton
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

5.  Detection of peroxisomal fatty acyl-coenzyme A oxidase activity.

Authors:  N C Inestrosa; M Bronfman; F Leighton
Journal:  Biochem J       Date:  1979-09-15       Impact factor: 3.857

6.  Factors influencing palmitoyl-CoA oxidation by rat liver peroxisomal fractions. Substrate concentration, organelle integrity and ATP.

Authors:  J Thomas; L J Debeer; P J De Schepper; G P Mannaerts
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

7.  Induction of hepatic peroxisome proliferation in nonrodent species, including primates.

Authors:  J K Reddy; N D Lalwani; S A Qureshi; M K Reddy; C M Moehle
Journal:  Am J Pathol       Date:  1984-01       Impact factor: 4.307

8.  Long-chain Acyl-CoA levels in liver from rats fed high-fat diets: is it of significance for an increased peroxisomal beta-oxidation?

Authors:  A Nilsson; M S Thomassen; E Christiansen
Journal:  Lipids       Date:  1984-03       Impact factor: 1.880

9.  Characterization of the stimulatory effect of high-fat diets on peroxisomal beta-oxidation in rat liver.

Authors:  M S Thomassen; E N Christiansen; K R Norum
Journal:  Biochem J       Date:  1982-08-15       Impact factor: 3.857

10.  Quantitative immunocytochemical studies on differential induction of serine:pyruvate aminotransferase in mitochondria and peroxisomes of rat liver cells by administration of glucagon or di-(2-ethylhexyl)phthalate.

Authors:  S Yokota
Journal:  Histochemistry       Date:  1986
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.