Literature DB >> 19533056

[Tonsillar actinomycosis as a rare cause of oral malodor. Diagnosis beyond a gastroenterologist's nose].

Christoph Lübbert1, Jörg G Albert, Michael Hainz, Annett Pudszuhn, Thomas Seufferlein.   

Abstract

BACKGROUND: Up to 30% of patients seen by dentists suffer from oral malodor. Part of them report serious distress and a sometimes paradoxical discrepancy in subjective and objective perception of symptoms. Less often, patients with oral malodor are primarily seen by general practitioners and specialists like gastroenterologists or ear, nose and throat (ENT) doctors. Correct characterization of the underlying disease and an adequate diagnosis are made most successfully through interdisciplinary cooperation. CASE REPORT: The case of a 43-year-old female patient is reported who presented with persistent oral malodor for > 1 year in the authors' outpatient department. Extensive diagnostic tests performed by various doctors in the past had not led to an adequate diagnosis and treatment. Clinical and laboratory examination in the authors' hospital showed normal findings apart from suspicion of chronic tonsillitis, confirmed by an ENT specialist. Therefore, tonsillectomy was performed. Histopathology revealed chronic tonsillitis with tonsillar actinomycosis but no other disease. 6 months after tonsillectomy the patient presented asymptomatic and comfortable. Oral malodor was no longer detectable.
CONCLUSION: Oral malodor has a broad differential diagnosis including chronic tonsillitis caused by Actinomyces species and concomitant anaerobic bacteria able to produce volatile sulphur compounds and other putrefactive molecules. Therapeutic gold standard in symptomatic disease is tonsillectomy, lacking comparative studies on the success rates of conservative antibiotic therapy, e.g., with aminopenicillins plus beta-lactamase inhibitor for several weeks or months. This case presentation illustrates that anticipated internal disease with an agonizing and prolonged cause of disease could be solved by tonsillectomy.

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Mesh:

Year:  2009        PMID: 19533056     DOI: 10.1007/s00063-009-1098-3

Source DB:  PubMed          Journal:  Med Klin (Munich)        ISSN: 0723-5003


  12 in total

1.  [Relation between actinomycosis infection and the occurrence of chronic tonsillitis in adults].

Authors:  P Janega; M Suly; P Babál
Journal:  Cesk Patol       Date:  2001-07

Review 2.  Oral malodour--a review.

Authors:  Francis J Hughes; Rod McNab
Journal:  Arch Oral Biol       Date:  2008-04       Impact factor: 2.633

3.  [Actinomyces as a causal agent of tonsillar pathology].

Authors:  V Miyar Villar; D Morais Pérez; M J Blasco Gutiérrez; G Martín Sigüenza
Journal:  Acta Otorrinolaringol Esp       Date:  1998 Aug-Sep

4.  The incidence and role of actinomyces in recurrent acute tonsillitis.

Authors:  R Gaffney; M Harrison; M Walsh; E Sweeney; M Cafferkey
Journal:  Clin Otolaryngol Allied Sci       Date:  1993-08

5.  Hydrogen sulfide-producing bacteria in tongue biofilm and their relationship with oral malodour.

Authors:  Jumpei Washio; Takuichi Sato; Takeyoshi Koseki; Nobuhiro Takahashi
Journal:  J Med Microbiol       Date:  2005-09       Impact factor: 2.472

6.  Correlation between volatile sulphur compounds and certain oral health measurements in the general population.

Authors:  H Miyazaki; S Sakao; Y Katoh; T Takehara
Journal:  J Periodontol       Date:  1995-08       Impact factor: 6.993

7.  Tonsillomycosis: a myco-histopathological study.

Authors:  A Maher; A Bassiouny; T J Bucci; M K Moawad; D S Hendawy
Journal:  J Laryngol Otol       Date:  1982-03       Impact factor: 1.469

8.  Bacteriologic findings in peritonsillar abscesses in young adults.

Authors:  H Jousimies-Somer; S Savolainen; A Mäkitie; J Ylikoski
Journal:  Clin Infect Dis       Date:  1993-06       Impact factor: 9.079

9.  An investigation of the significance of Actinomycosis in tonsil disease.

Authors:  Anton C van Lierop; C A J Prescott; Colin C Sinclair-Smith
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2007-10-04       Impact factor: 1.675

Review 10.  [Bad breath--aetiology, differential diagnosis and therapy].

Authors:  Thomas Imfeld
Journal:  Ther Umsch       Date:  2008-02
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