Literature DB >> 1953236

A case of propylene glycol toxic reaction associated with etomidate infusion.

E Bedichek1, B Kirschbaum.   

Abstract

For the treatment of postoperative seizures and prevention of brain edema, an etomidate drip was used in conjunction with phenytoin, diazepam, pentobarbital, and phenobarbital in a 70-year-old woman. During a period of 24 hours, the patient received in excess of 479 g of propylene glycol, which was present at 35% (vol/vol) concentration in the undiluted etomidate. The propylene glycol toxic reaction resolved after the infusion was stopped.

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Year:  1991        PMID： 1953236

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN： 0003-9926


  8 in total

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Review 6.  Drug-Induced Metabolic Acidosis.

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8.  E-cigarette constituents propylene glycol and vegetable glycerin decrease glucose uptake and its metabolism in airway epithelial cells in vitro.

Authors:  M Woodall; J Jacob; K K Kalsi; V Schroeder; E Davis; B Kenyon; I Khan; J P Garnett; R Tarran; D L Baines
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  8 in total

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