M Fernández Rivas1. 1. Allergology Service, Hospital Clínico San Carlos, Madrid, Spain. mfernandezri.hcsc@salud.madrid.org
Abstract
BACKGROUND: Alergológica-2005 is a cross-sectional study carried out in Spain in 4991 new patients prospectively recruited in allergy clinics. OBJECTIVE: To describe the characteristics of food allergic patients included in Alergológica-2005. RESULTS: Food allergy was diagnosed in 369 subjects (7.4%, 95% CI, 6.7%-8.1%). The most common offending foods were fruits (33.3% of cases), nuts (26%), shellfish (22%), egg (16%), milk (13.9%) and fish (9.8%). Rosaceae fruits and crustaceans elicited 23.6% and 18.7% of the reactions, respectively. Milk and egg were the most common foods in patients < 5 years of age, whereas fruits and nuts were the most prevalent foods in patients over 5 years. The most frequent manifestations included skin reactions (65.3%), oral allergy syndrome (33.6%), digestive symptoms (24.7%) and anaphylaxis (17.9%). The clinical presentation differed among foods. Prick-tests were carried out more frequently than serum immunoglobulin E (IgE) determinations (95.9% vs. 65%). Oral challenges were performed in 13% of patients, and 72.3% of these were open. Food allergy was diagnosed on the basis of medical history and positive IgE in 60.2% of the patients, ranging from 13.7% for milk to 75% for cereals. The self perception of patients' quality of life was lower than that of the 75% of Spanish reference population. CONCLUSION: Food allergy is diagnosed in 7.4% of the patients seen in allergy clinics across Spain, and has an important impact on the quality of life of patients. The foods involved in reactions change with age. The clinical presentation changes with the food, although the skin is the most frequently affected organ.
BACKGROUND: Alergológica-2005 is a cross-sectional study carried out in Spain in 4991 new patients prospectively recruited in allergy clinics. OBJECTIVE: To describe the characteristics of food allergicpatients included in Alergológica-2005. RESULTS: Food allergy was diagnosed in 369 subjects (7.4%, 95% CI, 6.7%-8.1%). The most common offending foods were fruits (33.3% of cases), nuts (26%), shellfish (22%), egg (16%), milk (13.9%) and fish (9.8%). Rosaceae fruits and crustaceans elicited 23.6% and 18.7% of the reactions, respectively. Milk and egg were the most common foods in patients < 5 years of age, whereas fruits and nuts were the most prevalent foods in patients over 5 years. The most frequent manifestations included skin reactions (65.3%), oral allergy syndrome (33.6%), digestive symptoms (24.7%) and anaphylaxis (17.9%). The clinical presentation differed among foods. Prick-tests were carried out more frequently than serum immunoglobulin E (IgE) determinations (95.9% vs. 65%). Oral challenges were performed in 13% of patients, and 72.3% of these were open. Food allergy was diagnosed on the basis of medical history and positive IgE in 60.2% of the patients, ranging from 13.7% for milk to 75% for cereals. The self perception of patients' quality of life was lower than that of the 75% of Spanish reference population. CONCLUSION: Food allergy is diagnosed in 7.4% of the patients seen in allergy clinics across Spain, and has an important impact on the quality of life of patients. The foods involved in reactions change with age. The clinical presentation changes with the food, although the skin is the most frequently affected organ.
Authors: Arantxa Palacín; Luis A Rivas; Cristina Gómez-Casado; Jacobo Aguirre; Leticia Tordesillas; Joan Bartra; Carlos Blanco; Teresa Carrillo; Javier Cuesta-Herranz; José A Cumplido Bonny; Enrique Flores; Mar G García-Alvarez-Eire; Ignacio García-Nuñez; Francisco J Fernández; Pedro Gamboa; Rosa Muñoz; Rosa Sánchez-Monge; Maria Torres; Susana Varela Losada; Mayte Villalba; Francisco Vega; Victor Parro; Miguel Blanca; Gabriel Salcedo; Araceli Díaz-Perales Journal: PLoS One Date: 2012-09-07 Impact factor: 3.240
Authors: Arantxa Palacín; Cristina Gómez-Casado; Luis A Rivas; Jacobo Aguirre; Leticia Tordesillas; Joan Bartra; Carlos Blanco; Teresa Carrillo; Javier Cuesta-Herranz; Consolación de Frutos; Genoveva García Alvarez-Eire; Francisco J Fernández; Pedro Gamboa; Rosa Muñoz; Rosa Sánchez-Monge; Sofía Sirvent; María J Torres; Susana Varela-Losada; Rosalía Rodríguez; Victor Parro; Miguel Blanca; Gabriel Salcedo; Araceli Díaz-Perales Journal: PLoS One Date: 2012-12-14 Impact factor: 3.240
Authors: Darío Antolín-Amérigo; Luis Manso; Marco Caminati; Belén de la Hoz Caballer; Inmaculada Cerecedo; Alfonso Muriel; Mercedes Rodríguez-Rodríguez; José Barbarroja-Escudero; María José Sánchez-González; Beatriz Huertas-Barbudo; Melchor Alvarez-Mon Journal: Clin Mol Allergy Date: 2016-02-17
Authors: Maria J Rodriguez; Ana Aranda; Tahia D Fernandez; Nuria Cubells-Baeza; Maria J Torres; Francisca Gomez; Francisca Palomares; James R Perkins; Javier Rojo; Araceli Diaz-Perales; Cristobalina Mayorga Journal: Sci Rep Date: 2017-01-13 Impact factor: 4.379
Authors: Susan L Prescott; Ruby Pawankar; Katrina J Allen; Dianne E Campbell; John Kh Sinn; Alessandro Fiocchi; Motohiro Ebisawa; Hugh A Sampson; Kirsten Beyer; Bee-Wah Lee Journal: World Allergy Organ J Date: 2013-12-04 Impact factor: 4.084