Literature DB >> 19528662

Darwin and the scientific method.

Francisco J Ayala1.   

Abstract

There is a contradiction between Darwin's methodology and how he described it for public consumption. Darwin claimed that he proceeded "on true Baconian [inductive] principles and without any theory collected facts on a wholesale scale." He also wrote, "How odd it is that anyone should not see that all observation must be for or against some view if it is to be of any service!" The scientific method includes 2 episodes. The first consists of formulating hypotheses; the second consists of experimentally testing them. What differentiates science from other knowledge is the second episode: subjecting hypotheses to empirical testing by observing whether or not predictions derived from a hypothesis are the case in relevant observations and experiments. A hypothesis is scientific only if it is consistent with some but not other possible states of affairs not yet observed, so that it is subject to the possibility of falsification by reference to experience. Darwin occupies an exalted place in the history of Western thought, deservedly receiving credit for the theory of evolution. In The Origin of Species, he laid out the evidence demonstrating the evolution of organisms. More important yet is that he discovered natural selection, the process that accounts for the adaptations of organisms and their complexity and diversification. Natural selection and other causal processes of evolution are investigated by formulating and testing hypotheses. Darwin advanced hypotheses in multiple fields, including geology, plant morphology and physiology, psychology, and evolution, and subjected them to severe empirical tests.

Mesh:

Year:  2009        PMID: 19528662      PMCID: PMC2702794          DOI: 10.1073/pnas.0901404106

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  5 in total

Review 1.  Split genes and RNA splicing.

Authors:  F Crick
Journal:  Science       Date:  1979-04-20       Impact factor: 47.728

2.  RNA-dependent DNA polymerase in virions of RNA tumour viruses.

Authors:  D Baltimore
Journal:  Nature       Date:  1970-06-27       Impact factor: 49.962

3.  RNA-dependent DNA polymerase in virions of Rous sarcoma virus.

Authors:  H M Temin; S Mizutani
Journal:  Nature       Date:  1970-06-27       Impact factor: 49.962

Review 4.  Self-splicing RNA: implications for evolution.

Authors:  T R Cech
Journal:  Int Rev Cytol       Date:  1985

5.  Split genes.

Authors:  P Chambon
Journal:  Sci Am       Date:  1981-05       Impact factor: 2.142

  5 in total
  10 in total

Review 1.  In the light of evolution III: two centuries of Darwin.

Authors:  John C Avise; Francisco J Ayala
Journal:  Proc Natl Acad Sci U S A       Date:  2009-06-15       Impact factor: 11.205

2.  Problem formulation and phenotypic characterisation for the development of novel crops.

Authors:  Alan Raybould
Journal:  Transgenic Res       Date:  2019-08       Impact factor: 2.788

3.  Severe testing with high-dimensional omics data for enhancing biomedical scientific discovery.

Authors:  Frank Emmert-Streib
Journal:  NPJ Syst Biol Appl       Date:  2022-10-21

Review 4.  How stands the Tree of Life a century and a half after The Origin?

Authors:  Maureen A O'Malley; Eugene V Koonin
Journal:  Biol Direct       Date:  2011-06-30       Impact factor: 4.540

5.  Popper and the Omics.

Authors:  Robert Winkler
Journal:  Front Plant Sci       Date:  2016-02-19       Impact factor: 5.753

6.  Perspective: Dimensions of the scientific method.

Authors:  Eberhard O Voit
Journal:  PLoS Comput Biol       Date:  2019-09-12       Impact factor: 4.475

7.  Scientific Thinking About Legal Truth.

Authors:  Gal Rosenzweig
Journal:  Front Psychol       Date:  2022-07-06

8.  When are hypotheses useful in ecology and evolution?

Authors:  Matthew G Betts; Adam S Hadley; David W Frey; Sarah J K Frey; Dusty Gannon; Scott H Harris; Hankyu Kim; Urs G Kormann; Kara Leimberger; Katie Moriarty; Joseph M Northrup; Ben Phalan; Josée S Rousseau; Thomas D Stokely; Jonathon J Valente; Chris Wolf; Diego Zárrate-Charry
Journal:  Ecol Evol       Date:  2021-03-25       Impact factor: 2.912

9.  The causes of variation in learning and behavior: why individual differences matter.

Authors:  Bruno Sauce; Louis D Matzel
Journal:  Front Psychol       Date:  2013-07-04

Review 10.  Influenza, evolution, and the next pandemic.

Authors:  David S Fedson
Journal:  Evol Med Public Health       Date:  2018-10-03
  10 in total

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