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Literature DB >> 19528276

oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.

Hong Bin Kim¹, Minghua Wang, Chi Hye Park, Eui-Chong Kim, George A Jacoby, David C Hooper.

Abstract

The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19528276 PMCID： PMC2715617 DOI： 10.1128/AAC.01574-08

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. qnr Gene nomenclature.

Authors: George Jacoby; Vincent Cattoir; David Hooper; Luis Martínez-Martínez; Patrice Nordmann; Alvaro Pascual; Laurent Poirel; Minggui Wang
Journal: Antimicrob Agents Chemother Date: 2008-04-21 Impact factor: 5.191

2. Development of PCR assays targeting the genes involved in synthesis and assembly of the new Escherichia coli O 174 and O 177 O antigens.

Authors: Lothar Beutin; Qingke Kong; Lu Feng; Quan Wang; Gladys Krause; Luciana Leomil; Qi Jin; Lei Wang
Journal: J Clin Microbiol Date: 2005-10 Impact factor: 5.948

3. A procedure for in vitro amplification of DNA segments that lie outside the boundaries of known sequences.

Authors: T Triglia; M G Peterson; D J Kemp
Journal: Nucleic Acids Res Date: 1988-08-25 Impact factor: 16.971

4. The prevalence of the OqxAB multidrug efflux pump amongst olaquindox-resistant Escherichia coli in pigs.

Authors: Lars Hestbjerg Hansen; Søren J Sørensen; Helle S Jørgensen; Lars B Jensen
Journal: Microb Drug Resist Date: 2005 Impact factor: 3.431

5. Plasmid-encoded multidrug efflux pump conferring resistance to olaquindox in Escherichia coli.

Authors: Lars Hestbjerg Hansen; Elsebetta Johannesen; Mette Burmølle; Anders Hay Sørensen; Søren J Sørensen
Journal: Antimicrob Agents Chemother Date: 2004-09 Impact factor: 5.191

6. Nucleotide sequence of pOLA52: a conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux.

Authors: Anders Norman; Lars Hestbjerg Hansen; Qunxin She; Søren Johannes Sørensen
Journal: Plasmid Date: 2008-04-28 Impact factor: 3.466

7. Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China.

Authors: Minggui Wang; John H Tran; George A Jacoby; Yingyuan Zhang; Fu Wang; David C Hooper
Journal: Antimicrob Agents Chemother Date: 2003-07 Impact factor: 5.191

8. Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period.

Authors: Hong Bin Kim; Chi Hye Park; Chung Jong Kim; Eui-Chong Kim; George A Jacoby; David C Hooper
Journal: Antimicrob Agents Chemother Date: 2008-12-08 Impact factor: 5.191

9. Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria.

Authors: Lars Hestbjerg Hansen; Lars Bogø Jensen; Heidi Iskou Sørensen; Søren Johannes Sørensen
Journal: J Antimicrob Chemother Date: 2007-05-24 Impact factor: 5.790

10. Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice.

Authors: Derrick E Fouts; Heather L Tyler; Robert T DeBoy; Sean Daugherty; Qinghu Ren; Jonathan H Badger; Anthony S Durkin; Heather Huot; Susmita Shrivastava; Sagar Kothari; Robert J Dodson; Yasmin Mohamoud; Hoda Khouri; Luiz F W Roesch; Karen A Krogfelt; Carsten Struve; Eric W Triplett; Barbara A Methé
Journal: PLoS Genet Date: 2008-07-25 Impact factor: 5.917

87 in total

1. Prevalence of qnr, aac(6')-Ib-cr, qepA, and oqxAB in Escherichia coli isolates from humans, animals, and the environment.

Authors: Xiang Chen; Weiqiu Zhang; Weijuan Pan; Jiajun Yin; Zhiming Pan; Song Gao; Xinan Jiao
Journal: Antimicrob Agents Chemother Date: 2012-03-05 Impact factor: 5.191

2. Characterization of RarA, a novel AraC family multidrug resistance regulator in Klebsiella pneumoniae.

Authors: Mark Veleba; Paul G Higgins; Gerardo Gonzalez; Harald Seifert; Thamarai Schneiders
Journal: Antimicrob Agents Chemother Date: 2012-05-29 Impact factor: 5.191

3. Identification of a Serratia marcescens clinical isolate with multiple quinolone resistance mechanisms from China.

Authors: Hai-Fei Yang; Jun Cheng; Li-Fen Hu; Ying Ye; Jia-Bin Li
Journal: Antimicrob Agents Chemother Date: 2012-08-13 Impact factor: 5.191

4. A fluoroquinolone-resistant Escherichia coli clinical isolate without quinolone resistance-determining region mutations found in Japan.

Authors: Toyotaka Sato; Shin-ichi Yokota; Ikuo Uchida; Torahiko Okubo; Kanako Ishihara; Nobuhiro Fujii; Yutaka Tamura
Journal: Antimicrob Agents Chemother Date: 2011-06-13 Impact factor: 5.191