Literature DB >> 19528045

A prospective cohort study of exposure-response relationship for vibration-induced white finger.

M Bovenzi1.   

Abstract

OBJECTIVES: To investigate prospectively the relation between vibration-induced white finger (VWF) and measures of cumulative (lifetime) exposure to hand-transmitted vibration (HTV).
METHODS: Two hundred and forty-nine HTV workers and 138 control men of the same companies participated in a 3-year follow-up study. The diagnosis of VWF (Raynaud's phenomenon in the controls) was based on the medical history, the administration of colour charts and the results of a cold test. Tool vibration magnitudes were expressed as root-mean-square (r.m.s.) acceleration, frequency-weighted according to international standard ISO 5349-1 and also unweighted over the frequency range 6.3-1250 Hz. From the vibration magnitudes and exposure durations, alternative measures of cumulative vibration dose were calculated for each HTV worker, according to the expression: dose = Sigmaa(i)(m)t(i), where a(i) is the acceleration magnitude on tool i, t(i) is the lifetime exposure duration (hours) for tool i, and m = 0, 1, 2 or 4.
RESULTS: The incidence of VWF varied from 5 to 6% in the HTV workers versus 0 to 1.5% for Raynaud's phenomenon in the controls. After adjusting for potential confounders, measures of cumulative vibration dose derived from total operating hours and high powers of unweighted acceleration (ie, , with m>1) gave better predictions of the occurrence of VWF than dose measures calculated from frequency-weighted acceleration (ie, ). These findings were observed in the entire sample of HTV workers, in those with no VWF at the initial investigation, and in those with normal cold test results at baseline.
CONCLUSIONS: This prospective cohort study suggests that measures of cumulative vibration doses constructed from unweighted r.m.s. acceleration perform better for the prediction of VWF than dose measures calculated according to the recommendations of current standards. These findings should contribute to the improvement of the ISO frequency weighting for evaluating the severity of hand-transmitted vibration.

Entities:  

Mesh:

Year:  2009        PMID: 19528045     DOI: 10.1136/oem.2009.046128

Source DB:  PubMed          Journal:  Occup Environ Med        ISSN: 1351-0711            Impact factor:   4.402


  8 in total

1.  Reduction in finger blood flow induced by hand-transmitted vibration: effect of hand elevation.

Authors:  Ying Ye; Marcella Mauro; Massimo Bovenzi; Michael J Griffin
Journal:  Int Arch Occup Environ Health       Date:  2015-02-08       Impact factor: 3.015

2.  Relation between vibrotactile perception thresholds and reductions in finger blood flow induced by vibration of the hand at frequencies in the range 8-250 Hz.

Authors:  Ying Ye; Michael J Griffin
Journal:  Eur J Appl Physiol       Date:  2014-04-29       Impact factor: 3.078

3.  A longitudinal study of neck and upper limb musculoskeletal disorders and alternative measures of vibration exposure.

Authors:  Massimo Bovenzi; Andrea Prodi; Marcella Mauro
Journal:  Int Arch Occup Environ Health       Date:  2016-04-18       Impact factor: 3.015

Review 4.  Health effects associated with occupational exposure to hand-arm or whole body vibration.

Authors:  Kristine Krajnak
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2018-12-25       Impact factor: 6.393

5.  Frequency-dependent changes in mitochondrial number and generation of reactive oxygen species in a rat model of vibration-induced injury.

Authors:  Kristine Krajnak
Journal:  J Toxicol Environ Health A       Date:  2020-01-23

Review 6.  Hand-arm vibration and the risk of vascular and neurological diseases-A systematic review and meta-analysis.

Authors:  Tohr Nilsson; Jens Wahlström; Lage Burström
Journal:  PLoS One       Date:  2017-07-13       Impact factor: 3.240

7.  Application of cold intolerance symptom severity questionnaire among vibration-exposed workers as a screening tool for the early detection of hand-arm vibration syndrome: a cross-sectional study.

Authors:  A Ram Kim; Dae Yun Kim; Ji Soo Kim; Heun Lee; Joo Hyun Sung; Cheolin Yoo
Journal:  Ann Occup Environ Med       Date:  2019-03-01

8.  Arterial abnormalities in the hands of workers with vibration white fingers - a magnetic resonance angiography case series.

Authors:  Per Vihlborg; Karim Makdomi; Hana Gavlovská; Sverre Wikström; Pål Graff
Journal:  J Occup Med Toxicol       Date:  2021-07-29       Impact factor: 2.646

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.