Literature DB >> 195279

Gynaecomastia associated with gonadotrophin-secreting carcinoma of the lung.

D Fairlamb, E Boesen.   

Abstract

A 67-year-old man developed dermatomyositis. Investigation revealed an oat cell carcinoma of the lung. When he developed unilateral gynaecomastia this tumour was found to secrete gonadotrophins. The gynaecomastia disappeared after treatment with an anti-oestrogen--tamoxifen. This use of tamoxifen has not previously been described. Partial tumour regression was obtained with several cytotoxic drug regimes. His dermatomyositis responded to this treatment and remains in remission.

Entities:  

Mesh:

Substances:

Year:  1977        PMID: 195279      PMCID: PMC2496563          DOI: 10.1136/pgmj.53.619.269

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  18 in total

1.  Gynecomastia; the origins of mammary swelling in the male: an analysis of 406 patients with breast hypertrophy, 525 with testicular tumors, and 13 with adrenal neoplasms.

Authors:  N TREVES
Journal:  Cancer       Date:  1958 Nov-Dec       Impact factor: 6.860

2.  Dermatomyositis and malignancy: a review of the literature.

Authors:  R C WILLIAMS
Journal:  Ann Intern Med       Date:  1959-05       Impact factor: 25.391

3.  Dermatomyositis as an index of malignant neoplasm: report of a case and review of the literature.

Authors:  M J BRUNNER; R V LOBRAICO
Journal:  Ann Intern Med       Date:  1951-05       Impact factor: 25.391

4.  Anti-oestrogen therapy for breast cancer: a trial of tamoxifen at two dose levels.

Authors:  H W Ward
Journal:  Br Med J       Date:  1973-01-06

5.  Estrogen production and its origin in men with gonadotropin-producing neoplasms.

Authors:  M A Kirschner; F B Cohen; D Jespersen
Journal:  J Clin Endocrinol Metab       Date:  1974-07       Impact factor: 5.958

6.  Treatment of dermatomyositis with methotrexate.

Authors:  A N Malaviya; A Many; R S Schwartz
Journal:  Lancet       Date:  1968-08-31       Impact factor: 79.321

7.  Gynaecomastia.

Authors:  J Ginsburg
Journal:  Practitioner       Date:  1969-08

8.  Treatment of corticosteroid-resistant polymyositis with methotrexate.

Authors:  M C Sokoloff; L S Goldberg; C M Pearson
Journal:  Lancet       Date:  1971-01-02       Impact factor: 79.321

9.  Gonadotropin-producing anaplastic large-cell carcinomas of the lung.

Authors:  F D Fusco; S W Rosen
Journal:  N Engl J Med       Date:  1966-09-08       Impact factor: 91.245

10.  Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases.

Authors:  H J Bloom; E Boesen
Journal:  Br Med J       Date:  1974-04-06
View more
  1 in total

1.  Dermatomyositis Associated with Lung Neuroendocrine Carcinoma.

Authors:  Reina Takashima; Kazufumi Takamatsu; Yutaka Shinkawa; Masato Yagita; Motonari Fukui; Masaaki Fujita
Journal:  Intern Med       Date:  2017-03-17       Impact factor: 1.271

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.