Xia Liu1, Yong Liu, Yanping Shi. 1. Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Abstract
OBJECTIVE: To isolate and identify the active xanthone glycosides in Halenia elliptica. METHOD: The compounds were isolated by column chromatography, semi-preparative high performance liquid chromatography and related techniques. Their structures were elucidated through spectroscopic analysis (NMR and MS). RESULT: Six xanthone glycosides were isolated and identified as: 2,3,5-trimethoxy-1-O-primeverosyloxyxanthone (1), 2, 3, 4, 5-tetramethoxy-1-O-primeverosyloxyxanthone (2), 2, 3, 5, 7-tetramethoxy-1-O-primeverosyloxyxanthone (3), 2, 3, 7-trimethoxy-1-O-primeverosyloxyxanthone (4), 2, 3, 4, 7-tetramethoxy-1-O-primeverosyloxyxanthone (5), and 2, 3, 4, 5, 7-pentamethoxy-1-O-primeverosyloxyxanthone (6). CONCLUSION: Compounds 4-6 were isolated from this plant for the first time.
OBJECTIVE: To isolate and identify the active xanthone glycosides in Halenia elliptica. METHOD: The compounds were isolated by column chromatography, semi-preparative high performance liquid chromatography and related techniques. Their structures were elucidated through spectroscopic analysis (NMR and MS). RESULT: Six xanthone glycosides were isolated and identified as: 2,3,5-trimethoxy-1-O-primeverosyloxyxanthone (1), 2, 3, 4, 5-tetramethoxy-1-O-primeverosyloxyxanthone (2), 2, 3, 5, 7-tetramethoxy-1-O-primeverosyloxyxanthone (3), 2, 3, 7-trimethoxy-1-O-primeverosyloxyxanthone (4), 2, 3, 4, 7-tetramethoxy-1-O-primeverosyloxyxanthone (5), and 2, 3, 4, 5, 7-pentamethoxy-1-O-primeverosyloxyxanthone (6). CONCLUSION: Compounds 4-6 were isolated from this plant for the first time.