Huizheng Fu1, Yongming Luo, Dongming Zhang. 1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Abstract
OBJECTIVE: To study the chemical constituents of the leaves of Psidium guajava. METHOD: The chemical constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and MPLC. Their structures were elucidated on the basis of spectral analysis. RESULT: Nine compounds were isolated from this plant, and the structure of them were identified as ursolic acid (1), 2alpha-hydroxyursolic acid (2), 2alpha-hydroxyoleanolic acid (3), morin-3-O-alpha-L-arabopyranoside (4), quercetin (5), hyperin (6), myricetin-3-O-beta-D-glucoside (7), quercetin-3-O-beta-D-glucuronopyranoside (8), 1-O-galloyl-beta-D-glucose (9). CONCLUSION: Compounds 3, 7-9 were isolated from this plant for the first time.
OBJECTIVE: To study the chemical constituents of the leaves of Psidium guajava. METHOD: The chemical constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and MPLC. Their structures were elucidated on the basis of spectral analysis. RESULT: Nine compounds were isolated from this plant, and the structure of them were identified as ursolic acid (1), 2alpha-hydroxyursolic acid (2), 2alpha-hydroxyoleanolic acid (3), morin-3-O-alpha-L-arabopyranoside (4), quercetin (5), hyperin (6), myricetin-3-O-beta-D-glucoside (7), quercetin-3-O-beta-D-glucuronopyranoside (8), 1-O-galloyl-beta-D-glucose (9). CONCLUSION: Compounds 3, 7-9 were isolated from this plant for the first time.
Authors: Abdur Rauf; Muhammad Akram; Prabhakar Semwal; Adil A H Mujawah; Naveed Muhammad; Zerfishan Riaz; Naveed Munir; Dmitry Piotrovsky; Irina Vdovina; Abdelhakim Bouyahya; Charles Oluwaseun Adetunji; Mohammad Ali Shariati; Zainab M Almarhoon; Yahia N Mabkhot; Haroon Khan Journal: Oxid Med Cell Longev Date: 2021-11-11 Impact factor: 6.543