Literature DB >> 19524502

Prion topology and toxicity.

Adriano Aguzzi1, Andrew D Steele.   

Abstract

Inactivation of mahogunin, an E3 ubiquitin ligase, causes a spongiform encephalopathy resembling prion disease. Chakrabarti and Hegde (2009) now report that prion proteins with aberrant topologies inactivate mahogunin, providing a plausible explanation for certain aspects of prion pathology.

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Year:  2009        PMID： 19524502     DOI： 10.1016/j.cell.2009.05.041

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  4 in total

1.  Effect of divalent metals on the neuronal proteasomal system, prion protein ubiquitination and aggregation.

Authors:  A G Kanthasamy; C Choi; H Jin; D S Harischandra; V Anantharam; A Kanthasamy
Journal:  Toxicol Lett       Date:  2012-09-17       Impact factor: 4.372

Review 2.  Prion propagation, toxicity and degradation.

Authors:  Adriano Aguzzi; Jeppe Falsig
Journal:  Nat Neurosci       Date:  2012-06-26       Impact factor: 24.884

3.  Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2.

Authors:  Emiliano Zamponi; Fiamma Buratti; Gabriel Cataldi; Hector Hugo Caicedo; Yuyu Song; Lisa M Jungbauer; Mary J LaDu; Mariano Bisbal; Alfredo Lorenzo; Jiyan Ma; Pablo R Helguera; Gerardo A Morfini; Scott T Brady; Gustavo F Pigino
Journal:  PLoS One       Date:  2017-12-20       Impact factor: 3.240

4.  Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle.

Authors:  Taner Dogan; Florian Gnad; Jocelyn Chan; Lilian Phu; Amy Young; Mark J Chen; Sophia Doll; Matthew P Stokes; Marcia Belvin; Lori S Friedman; Donald S Kirkpatrick; Klaus P Hoeflich; Georgia Hatzivassiliou
Journal:  J Biol Chem       Date:  2017-06-27       Impact factor: 5.157
  4 in total

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