BACKGROUND: Previous studies have shown that exaggerated blood pressure (BP) during exercise is a valid risk predictor for future hypertension in most men and women, yet the use of ergometry as a means of early detection of incipient hypertension still requires confirmation. OBJECTIVES: To assess the clinical utility of exercise BP measurement for the evaluation of risk for developing new-onset hypertension. METHODS: Thirty individuals with normal BP were enrolled in this study and were subsequently divided into two groups: 13 persons with in-exercise hypertension were compared with 17 matched persons who were normotensive during ergometry. Their blood pressure was monitored during follow-up of two years. RESULTS: More individuals in the exercise-hypertensive group developed hypertension after one or two years than those normotensive during the exercise (respectively, one year: 3 vs.0, p=0.03, two years: 10 vs. 1, p<0.0001). Both the systolic and diastolic BPs significantly differed between the two groups. Eighty four percent of those with exaggerated BP (>or=210 mm Hg) during the treadmill exercise developed hypertension after 2 years. The sensitivity and specificity of in-exercise hypertension for predicting its 2 year occurrence were, respectively, 91% and 84%. CONCLUSION: Even in the absence of hypertension, its development during stress ergometry could be considered a predictive marker for the future development of hypertension, and can be a potential tool for identifying normotensive individuals at high risk. These individuals should be followed up and their BP controlled for a long time.
BACKGROUND: Previous studies have shown that exaggerated blood pressure (BP) during exercise is a valid risk predictor for future hypertension in most men and women, yet the use of ergometry as a means of early detection of incipient hypertension still requires confirmation. OBJECTIVES: To assess the clinical utility of exercise BP measurement for the evaluation of risk for developing new-onset hypertension. METHODS: Thirty individuals with normal BP were enrolled in this study and were subsequently divided into two groups: 13 persons with in-exercise hypertension were compared with 17 matched persons who were normotensive during ergometry. Their blood pressure was monitored during follow-up of two years. RESULTS: More individuals in the exercise-hypertensive group developed hypertension after one or two years than those normotensive during the exercise (respectively, one year: 3 vs.0, p=0.03, two years: 10 vs. 1, p<0.0001). Both the systolic and diastolic BPs significantly differed between the two groups. Eighty four percent of those with exaggerated BP (>or=210 mm Hg) during the treadmill exercise developed hypertension after 2 years. The sensitivity and specificity of in-exercise hypertension for predicting its 2 year occurrence were, respectively, 91% and 84%. CONCLUSION: Even in the absence of hypertension, its development during stress ergometry could be considered a predictive marker for the future development of hypertension, and can be a potential tool for identifying normotensive individuals at high risk. These individuals should be followed up and their BP controlled for a long time.
Authors: Vernon Bond; Bryan H Curry; R George Adams; M Sadegh Asadi; Kimani A Stancil; Richard M Millis; Georges E Haddad Journal: ISRN Physiol Date: 2014-02-23
Authors: S G Lima; M F P M Albuquerque; J R M Oliveira; C F J Ayres; J E G Cunha; D F Oliveira; R R Lemos; M B R Souza; O Barbosa e Silva Journal: Braz J Med Biol Res Date: 2013-04-19 Impact factor: 2.590
Authors: Akothirene C Dutra-Marques; Sara Rodrigues; Felipe X Cepeda; Edgar Toschi-Dias; Eduardo Rondon; Jefferson C Carvalho; Maria Janieire N N Alves; Ana Maria F W Braga; Maria Urbana P B Rondon; Ivani C Trombetta Journal: Front Neurosci Date: 2021-06-09 Impact factor: 4.677