Literature DB >> 19524038

The origin of the genetic code and of the earliest oligopeptides.

Edward N Trifonov1.   

Abstract

Reconstruction of the earliest proteins in the ancient binary alphabet [glycine family G, alanine family A] leads to repeats of G alternating with repeats of A. In addition, omnipresent motifs can be assembled in two of the earliest genes involved in energy supply, crucial for Life, i.e. ATP/GTP binding and ATPase activity. They are an almost perfect match to the alternating G and A and are complementary to each other.

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Year:  2009        PMID: 19524038     DOI: 10.1016/j.resmic.2009.05.004

Source DB:  PubMed          Journal:  Res Microbiol        ISSN: 0923-2508            Impact factor:   3.992


  10 in total

1.  Modern diversification of the amino acid repertoire driven by oxygen.

Authors:  Matthias Granold; Parvana Hajieva; Monica Ioana Toşa; Florin-Dan Irimie; Bernd Moosmann
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-19       Impact factor: 11.205

Review 2.  Probing the Role of Cysteine Thiyl Radicals in Biology: Eminently Dangerous, Difficult to Scavenge.

Authors:  Bernd Moosmann; Parvana Hajieva
Journal:  Antioxidants (Basel)       Date:  2022-04-29

3.  Uniquely localized intra-molecular amino acid concentrations at the glycolytic enzyme catalytic/active centers of Archaea, Bacteria and Eukaryota are associated with their proposed temporal appearances on earth.

Authors:  J Dennis Pollack; David Gerard; Dennis K Pearl
Journal:  Orig Life Evol Biosph       Date:  2013-05-29       Impact factor: 1.950

4.  On the observable transition to living matter.

Authors:  Samanta Pino; Edward N Trifonov; Ernesto Di Mauro
Journal:  Genomics Proteomics Bioinformatics       Date:  2011-04       Impact factor: 7.691

5.  Evolution of Nucleotide Punctuation Marks: From Structural to Linear Signals.

Authors:  Nawal El Houmami; Hervé Seligmann
Journal:  Front Genet       Date:  2017-03-27       Impact factor: 4.599

Review 6.  Functional and protective hole hopping in metalloenzymes.

Authors:  Harry B Gray; Jay R Winkler
Journal:  Chem Sci       Date:  2021-09-27       Impact factor: 9.825

7.  From amino acid mixtures to peptides in liquid sulphur dioxide on early Earth.

Authors:  Fabian Sauer; Maren Haas; Constanze Sydow; Alexander F Siegle; Christoph A Lauer; Oliver Trapp
Journal:  Nat Commun       Date:  2021-12-10       Impact factor: 14.919

8.  RNP-world: The ultimate essence of life is a ribonucleoprotein process.

Authors:  Sávio Torres de Farias; Francisco Prosdocimi
Journal:  Genet Mol Biol       Date:  2022-09-23       Impact factor: 2.087

9.  Dissecting the role of low-complexity regions in the evolution of vertebrate proteins.

Authors:  Núria Radó-Trilla; Mmar Albà
Journal:  BMC Evol Biol       Date:  2012-08-24       Impact factor: 3.260

10.  Low complexity regions in the proteins of prokaryotes perform important functional roles and are highly conserved.

Authors:  Chrysa Ntountoumi; Panayotis Vlastaridis; Dimitris Mossialos; Constantinos Stathopoulos; Ioannis Iliopoulos; Vasilios Promponas; Stephen G Oliver; Grigoris D Amoutzias
Journal:  Nucleic Acids Res       Date:  2019-11-04       Impact factor: 16.971

  10 in total

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