Literature DB >> 19521750

Immobilization of RGD peptide on HA coating through a chemical bonding approach.

Chunli Yang1, Kui Cheng, Wenjian Weng, Chunyu Yang.   

Abstract

In this work, Arg-Gly-Asp (RGD) sequence containing peptide was immobilized on hydroxyapatite (HA) coatings through a chemical bonding approach in two steps, surface modification with 3-aminopropyltriethoxysilane (APTES) and RGD immobilization. The results indicate that RGD has been successfully immobilized on HA coatings. Comparing with physical adsorption coatings, the chemically bonded RGD on the coatings shows much better anti-wash-out ability. Since RGD is able to recognize cell-membrane integrins on biointerfaces, the present method will be an effective way to favor interaction of cells with HA coatings.

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Year:  2009        PMID： 19521750     DOI： 10.1007/s10856-009-3794-1

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN： 0957-4530            Impact factor:   3.896


  17 in total

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Journal:  J Biomed Mater Res       Date:  2001-11

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Journal:  J Cell Sci       Date:  1998-02       Impact factor: 5.285
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  10 in total

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7.  The impact of the RGD peptide on osteoblast adhesion and spreading on zinc-substituted hydroxyapatite surface.

Authors:  Elena Mavropoulos; Moema Hausen; Andrea M Costa; Gutemberg Alves; Alexandre Mello; C A Ospina; M Mir; José M Granjeiro; Alexandre M Rossi
Journal:  J Mater Sci Mater Med       Date:  2013-03-14       Impact factor: 3.896

8.  A novel cyclic RGD-containing peptide polymer improves serum-free adhesion of adipose tissue-derived mesenchymal stem cells to bone implant surfaces.

Authors:  Péter Tátrai; Bernadett Sági; Anna Szigeti; Aron Szepesi; Ildikó Szabó; Szilvia Bősze; Zoltán Kristóf; Károly Markó; Gergely Szakács; István Urbán; Gábor Mező; Ferenc Uher; Katalin Német
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Journal:  PLoS One       Date:  2014-12-11       Impact factor: 3.240
  10 in total

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