Literature DB >> 19521142

Gender differences in axis I and axis II comorbidity in patients with borderline personality disorder.

André Tadić1, Stefanie Wagner, Julia Hoch, Omur Başkaya, Robert von Cube, Christian Skaletz, Klaus Lieb, Norbert Dahmen.   

Abstract

BACKGROUND/AIMS: Differences in the clinical presentation of men and women with borderline personality disorder (BPD) are of potential interest for investigations into the neurobiology, genetics, natural history, and treatment response of BPD. The purpose of this study was to investigate gender differences in axis I and axis II comorbidity and in diagnostic criteria in BPD patients.
METHODS: 110 women and 49 men with BPD were assessed with the computer-based version of the Munich-Composite International Diagnostic Interview and the Structured Clinical Interview for DSM-IV Personality Disorders. Gender differences were investigated for the following outcomes: (a) lifetime, 12-month and 4-week prevalence of axis I disorders; (b) axis II disorders, and (c) DSM-IV BPD diagnostic criteria.
RESULTS: With regard to lifetime prevalence of axis I disorders, men more often displayed a substance use disorder, in particular alcohol dependency (65 vs. 43%); on the other hand, women more frequently had an affective (94 vs. 82%), anxiety (92 vs. 80%) or eating disorder (35 vs. 18%), in particular anorexia nervosa (21 vs. 4%). Regarding the 12-month prevalence, we found significantly more women suffering from anorexia nervosa (13 vs. 0%). Considering the 4-week prevalence, there were no significant gender differences. With regard to axis II disorders, men had a higher frequency of antisocial personality disorder (57 vs. 26%). Regarding the BPD diagnostic criteria, men more often displayed 'intensive anger' (74 vs. 49%), whereas women more frequently showed 'affective instability' (94 vs. 82%).
CONCLUSION: In this German study, we could replicate and extend the findings from previous US studies, where men and women with BPD showed important differences in their pattern of psychiatric comorbidity. The implications for clinicians and researchers are discussed. 2009 S. Karger AG, Basel.

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Year:  2009        PMID: 19521142     DOI: 10.1159/000224149

Source DB:  PubMed          Journal:  Psychopathology        ISSN: 0254-4962            Impact factor:   1.944


  17 in total

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Authors:  Randy A Sansone; Lori A Sansone
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2.  The abuse of prescription medications in borderline personality disorder: a gender comparison.

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4.  Eating disorder symptoms and borderline personality symptomatology.

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Journal:  Eat Weight Disord       Date:  2011-06       Impact factor: 4.652

Review 5.  Sex difference in alcoholism: who is at a greater risk for development of alcoholic complication?

Authors:  Asli F Ceylan-Isik; Shawna M McBride; Jun Ren
Journal:  Life Sci       Date:  2010-06-16       Impact factor: 5.037

6.  Gender patterns in borderline personality disorder.

Authors:  Randy A Sansone; Lori A Sansone
Journal:  Innov Clin Neurosci       Date:  2011-05

7.  The impact of borderline personality disorder on residential substance abuse treatment dropout among men.

Authors:  Matthew T Tull; Kim L Gratz
Journal:  Drug Alcohol Depend       Date:  2011-09-09       Impact factor: 4.492

8.  A psychometric investigation of gender differences and common processes across borderline and antisocial personality disorders.

Authors:  Seokjoon Chun; Alexa Harris; Margely Carrion; Elizabeth Rojas; Stephen Stark; Carl Lejuez; William V Lechner; Marina A Bornovalova
Journal:  J Abnorm Psychol       Date:  2016-11-03

Review 9.  Sexually dimorphic role of circadian clock genes in alcohol drinking behavior.

Authors:  Nuria de Zavalia; Sarah Ferraro; Shimon Amir
Journal:  Psychopharmacology (Berl)       Date:  2022-10-03       Impact factor: 4.415

10.  An investigation of the relationship between borderline personality disorder and cocaine-related attentional bias following trauma cue exposure: the moderating role of gender.

Authors:  Joseph R Bardeen; Katherine L Dixon-Gordon; Matthew T Tull; Judith A Lyons; Kim L Gratz
Journal:  Compr Psychiatry       Date:  2013-10-17       Impact factor: 3.735

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