Literature DB >> 19517256

Can metabolic abnormalities after a fall predict short term mortality in elderly patients?

Frédéric Bloch1, David Jegou, Jean-François Dhainaut, Anne-Sophie Rigaud, Joël Coste, Jean-Eric Lundy, Yann-Erick Claessens.   

Abstract

Morbidity related is important in older adults who fall and are consequently referred to emergency departments (ED). The aim of this study is to determine 6-month all-causes mortality in patients over 75 years referred to an emergency department after a fall at home, and to define the criteria associated with death. The design was a prospective observational study with a 6-month follow-up in an Emergency Department of a tertiary teaching hospital, Paris, France. We included for a 6-month period patients over 75 years who visited the Emergency Department for a fall that occurred at home and measured the 6-month all-causes mortality. Uni- and multivariate assessment of factors related to mortality were adjusted for the occurrence of trauma. We enrolled 433 patients. Mean age was 86 years and two-thirds were women. The population was in relatively good health and preserved autonomy. The prevailing consequence was trauma and 11% had metabolic disorders. 64 patients (15%) died within 6 months. Factors associated with mortality included decrease in Katz score, male gender, a fall of intrinsic origin and the occurrence of adverse metabolic events. Markers of fragility such as poor previous level of autonomy, clinical disorders and metabolic abnormalities, as cause or consequence, indicate a potentially poor outcome more than the presence of severe trauma. As metabolic abnormalities can be an indirect marker of a long delay before emergency medical care, this study underscored the importance of early warning system for the frailest old individuals in order to prevent such complications.

Entities:  

Mesh:

Year:  2009        PMID: 19517256     DOI: 10.1007/s10654-009-9342-y

Source DB:  PubMed          Journal:  Eur J Epidemiol        ISSN: 0393-2990            Impact factor:   8.082


  16 in total

1.  STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION.

Authors:  S KATZ; A B FORD; R W MOSKOWITZ; B A JACKSON; M W JAFFE
Journal:  JAMA       Date:  1963-09-21       Impact factor: 56.272

Review 2.  Preventing falls and subsequent injury in older people.

Authors:  A Oakley; M F Dawson; J Holland; S Arnold; C Cryer; Y Doyle; J Rice; C R Hodgson; A Sowden; T Sheldon; D Fullerton; A M Glenny; A Eastwood
Journal:  Qual Health Care       Date:  1996-12

Review 3.  Prevention of falls among the elderly.

Authors:  M E Tinetti; M Speechley
Journal:  N Engl J Med       Date:  1989-04-20       Impact factor: 91.245

Review 4.  Systematic review of definitions and methods of measuring falls in randomised controlled fall prevention trials.

Authors:  Klaus Hauer; Sarah E Lamb; Ellen C Jorstad; Chris Todd; Clemens Becker
Journal:  Age Ageing       Date:  2006-01       Impact factor: 10.668

5.  A longitudinal study of functional change and mortality in the United States.

Authors:  K G Manton
Journal:  J Gerontol       Date:  1988-09

Review 6.  Falls, a community care perspective.

Authors:  C van Weel; H Vermeulen; W van den Bosch
Journal:  Lancet       Date:  1995-06-17       Impact factor: 79.321

Review 7.  Falls in the nursing home.

Authors:  L Z Rubenstein; K R Josephson; A S Robbins
Journal:  Ann Intern Med       Date:  1994-09-15       Impact factor: 25.391

8.  The incidence of fall injury events among the elderly in a defined population.

Authors:  R W Sattin; D A Lambert Huber; C A DeVito; J G Rodriguez; A Ros; S Bacchelli; J A Stevens; R J Waxweiler
Journal:  Am J Epidemiol       Date:  1990-06       Impact factor: 4.897

9.  The Israeli kibbutz as a venue for reduced disability in old age: lessons from the Cross-sectional and Longitudinal Aging Study (CALAS).

Authors:  Adrian Walter-Ginzburg; Tzvia Blumstein; Jack M Guralnik
Journal:  Soc Sci Med       Date:  2004-07       Impact factor: 4.634

10.  Mortality after the hospitalization of a spouse.

Authors:  Nicholas A Christakis; Paul D Allison
Journal:  N Engl J Med       Date:  2006-02-16       Impact factor: 91.245

View more
  6 in total

1.  The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design.

Authors:  Xin Gao; Albert Hofman; Yu Hu; Huandong Lin; Chouwen Zhu; Johannes Jeekel; Xuejuan Jin; Jiyao Wang; Jian Gao; Yiqing Yin; Naiqing Zhao
Journal:  Eur J Epidemiol       Date:  2010-12-01       Impact factor: 8.082

2.  New studies, technology, and the progress of epidemiology.

Authors:  Albert Hofman
Journal:  Eur J Epidemiol       Date:  2010-12       Impact factor: 8.082

3.  The Generation R Study: design and cohort update 2010.

Authors:  Vincent W V Jaddoe; Cock M van Duijn; Albert J van der Heijden; Johan P Mackenbach; Henriëtte A Moll; Eric A P Steegers; Henning Tiemeier; Andre G Uitterlinden; Frank C Verhulst; Albert Hofman
Journal:  Eur J Epidemiol       Date:  2010-10-22       Impact factor: 8.082

4.  The Rotterdam Study: 2012 objectives and design update.

Authors:  Albert Hofman; Cornelia M van Duijn; Oscar H Franco; M Arfan Ikram; Harry L A Janssen; Caroline C W Klaver; Ernst J Kuipers; Tamar E C Nijsten; Bruno H Ch Stricker; Henning Tiemeier; André G Uitterlinden; Meike W Vernooij; Jacqueline C M Witteman
Journal:  Eur J Epidemiol       Date:  2011-08-30       Impact factor: 8.082

5.  1H NMR Urinary Metabolomic Analysis in Older Adults after Hip Fracture Surgery May Provide Valuable Information for Patient Profiling-A Preliminary Investigation.

Authors:  Wafa Douzi; Delphine Bon; Sara Suikkanen; Paula Soukkio; Nadège Boildieu; Arja Nenonen; Markku Hupli; Katriina Kukkonen-Harjula; Benoit Dugué
Journal:  Metabolites       Date:  2022-08-12

6.  Screening Gait Performance, Falls, and Physical Activity among Benedictine and Trappist Monks.

Authors:  Dennis W Klima; Adam Davey
Journal:  J Prim Care Community Health       Date:  2021 Jan-Dec
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.