Literature DB >> 19517094

[Osteoarthritis--histopathologic diagnosis: typing, grading, and staging].

J Zustin1, T Aigner.   

Abstract

Osteoarthritis is one of the most common diseases in modern western societies, particularly in the elderly, but it is occurring more and more often in the younger and middle-aged population, especially after traumatic injuries. The classification and grading of changes during cartilage degeneration is difficult due to the notoriously high heterogeneity of the disease process and is only partly clinically relevant. Overall, the process of joint destruction can always be evaluated for the pathogenesis (typing), its extent (staging), and the degree of the most extensive focal damage (grading). However, in the clinical routine, description and reporting of the basic findings might be best restricted to specimens obtained from endoprosthetic surgery. Only the identification of previously unknown underlying conditions such as rheumatoid disease, gout, or extensive osteonecrosis is of particular clinical interest.

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Mesh:

Year:  2009        PMID: 19517094     DOI: 10.1007/s00132-008-1399-x

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  25 in total

Review 1.  Cell death in cartilage.

Authors:  K Kühn; D D D'Lima; S Hashimoto; M Lotz
Journal:  Osteoarthritis Cartilage       Date:  2004-01       Impact factor: 6.576

2.  Subtyping of osteoarthritic synoviopathy.

Authors:  S Oehler; D Neureiter; C Meyer-Scholten; T Aigner
Journal:  Clin Exp Rheumatol       Date:  2002 Sep-Oct       Impact factor: 4.473

Review 3.  Structure and function of cartilage collagens.

Authors:  P Bruckner; M van der Rest
Journal:  Microsc Res Tech       Date:  1994-08-01       Impact factor: 2.769

Review 4.  Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments.

Authors:  G A Homandberg
Journal:  Front Biosci       Date:  1999-10-15

5.  Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage.

Authors:  T Aigner; W Bertling; H Stöss; G Weseloh; K von der Mark
Journal:  J Clin Invest       Date:  1993-03       Impact factor: 14.808

Review 6.  Aging theories of primary osteoarthritis: from epidemiology to molecular biology.

Authors:  T Aigner; J Rose; J Martin; J Buckwalter
Journal:  Rejuvenation Res       Date:  2004       Impact factor: 4.663

7.  Morphologic alterations of the subchondral bone in advanced degenerative arthritis.

Authors:  J W Milgram
Journal:  Clin Orthop Relat Res       Date:  1983-03       Impact factor: 4.176

8.  Cluster analysis and display of genome-wide expression patterns.

Authors:  M B Eisen; P T Spellman; P O Brown; D Botstein
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

9.  Activation of collagen type II expression in osteoarthritic and rheumatoid cartilage.

Authors:  T Aigner; H Stöss; G Weseloh; G Zeiler; K von der Mark
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1992

10.  Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescence.

Authors:  Thomas Aigner; Stefan Söder; Pia M Gebhard; Audrey McAlinden; Jochen Haag
Journal:  Nat Clin Pract Rheumatol       Date:  2007-07
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  2 in total

1.  [Histological pathological investigations and arthroplasty: do they make sense?].

Authors:  J Schaumburger; P Lechler; J Grifka; M Fleck
Journal:  Z Rheumatol       Date:  2011-06       Impact factor: 1.372

Review 2.  [Fifteen years of the histopathological synovitis score : Review and further developments of a diagnostic score].

Authors:  V Krenn; G Perino; W Rüther; V T Krenn; M Huber; T Hügle; A Najm; S Müller; F Boettner; F Pessler; W Waldstein; J Kriegsmann; T Häupl; S Wienert; M G Krukemeyer; S Sesselmann; R Tikhilov; L Morawietz
Journal:  Z Rheumatol       Date:  2017-08       Impact factor: 1.372

  2 in total

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