Literature DB >> 19517084

[Central auditory prosthesis].

T Lenarz1, H Lim, G Joseph, G Reuter, M Lenarz.   

Abstract

Deaf patients with severe sensory hearing loss can benefit from a cochlear implant (CI), which stimulates the auditory nerve fibers. However, patients who do not have an intact auditory nerve cannot benefit from a CI. The majority of these patients are neurofibromatosis type 2 (NF2) patients who developed neural deafness due to growth or surgical removal of a bilateral acoustic neuroma. The only current solution is the auditory brainstem implant (ABI), which stimulates the surface of the cochlear nucleus in the brainstem. Although the ABI provides improvement in environmental awareness and lip-reading capabilities, only a few NF2 patients have achieved some limited open set speech perception. In the search for alternative procedures our research group in collaboration with Cochlear Ltd. (Australia) developed a human prototype auditory midbrain implant (AMI), which is designed to electrically stimulate the inferior colliculus (IC). The IC has the potential as a new target for an auditory prosthesis as it provides access to neural projections necessary for speech perception as well as a systematic map of spectral information. In this paper the present status of research and development in the field of central auditory prostheses is presented with respect to technology, surgical technique and hearing results as well as the background concepts of ABI and AMI.

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Year:  2009        PMID: 19517084     DOI: 10.1007/s00106-009-1944-x

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  25 in total

1.  No tissue damage by chronic deep brain stimulation in Parkinson's disease.

Authors:  C Haberler; F Alesch; P R Mazal; P Pilz; K Jellinger; M M Pinter; J A Hainfellner; H Budka
Journal:  Ann Neurol       Date:  2000-09       Impact factor: 10.422

2.  A genetic study of type 2 neurofibromatosis in the United Kingdom. I. Prevalence, mutation rate, fitness, and confirmation of maternal transmission effect on severity.

Authors:  D G Evans; S M Huson; D Donnai; W Neary; V Blair; D Teare; V Newton; T Strachan; R Ramsden; R Harris
Journal:  J Med Genet       Date:  1992-12       Impact factor: 6.318

3.  Cochlear nucleus implants.

Authors:  W E Hitselberger; W F House; B J Edgerton; S Whitaker
Journal:  Otolaryngol Head Neck Surg       Date:  1984-02       Impact factor: 3.497

4.  Auditory brainstem implant: part I. Auditory performance and its evolution over time.

Authors:  T Lenarz; M Moshrefi; C Matthies; C Frohne; A Lesinski-Schiedat; A Illg; U Rost; R D Battmer; M Samii
Journal:  Otol Neurotol       Date:  2001-11       Impact factor: 2.311

5.  Open set speech perception with auditory brainstem implant?

Authors:  Vittorio Colletti; Robert V Shannon
Journal:  Laryngoscope       Date:  2005-11       Impact factor: 3.325

6.  Chronic microstimulation in the feline ventral cochlear nucleus: physiologic and histologic effects.

Authors:  D B McCreery; T G Yuen; L A Bullara
Journal:  Hear Res       Date:  2000-11       Impact factor: 3.208

7.  The human auditory brain stem: a comparative view.

Authors:  J K Moore
Journal:  Hear Res       Date:  1987       Impact factor: 3.208

8.  Auditory brainstem implant part II: subjective assessment of functional outcome.

Authors:  Minoo Lenarz; Cordula Matthies; Anke Lesinski-Schiedat; Carolin Frohne; Urte Rost; Angelika Illg; Rolf D Battmer; Madjid Samii; Thomas Lenarz
Journal:  Otol Neurotol       Date:  2002-09       Impact factor: 2.311

Review 9.  Cochlear implants: selection criteria and shifting borders.

Authors:  T Lenarz
Journal:  Acta Otorhinolaryngol Belg       Date:  1998

10.  Electrical stimulation of the midbrain for hearing restoration: insight into the functional organization of the human central auditory system.

Authors:  Hubert H Lim; Thomas Lenarz; Gert Joseph; Rolf-Dieter Battmer; Amir Samii; Madjid Samii; James F Patrick; Minoo Lenarz
Journal:  J Neurosci       Date:  2007-12-05       Impact factor: 6.167

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  3 in total

1.  [Which colours can we hear?: light stimulation of the hearing system].

Authors:  G I Wenzel; T Lenarz; B Schick
Journal:  HNO       Date:  2014-02       Impact factor: 1.284

Review 2.  Cochlear implant - state of the art.

Authors:  Thomas Lenarz
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2018-02-19

3.  Necrotizing fasciitis in three university hospitals in Korea: a change in causative microorganisms and risk factors of mortality during the last decade.

Authors:  Shi Nae Yu; Tae Hyong Kim; Eun Jung Lee; Eun-Joo Choo; Min Hyok Jeon; Yung Gyu Jung; Tae Jin Kim; In Ki Mun; Ji Sung Lee
Journal:  Infect Chemother       Date:  2013-12-27
  3 in total

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