RATIONALE: A recent study showed that doctors are excessively pessimistic about the prognosis in patients with COPD and suggested that a simple tool to predict outcome is needed. METHODS: In a prospective observational study, 3343 patients with an FEV1<80% of the predicted value and FEV1/FVC<70% were selected from a clinical network of patients screened for COPD in Tayside, Scotland. Data were collected during annual visits on demography, spirometry, smoking history, medical research council (MRC) dyspnoea scale, body mass index (BMI) and other variables. The main outcome measures were hospitalisations and death secondary to COPD. A proportional hazard model was used to identify significant risk factors. RESULTS: Increasing age, low BMI, worsening MRC dyspnoea score, decreased FEV1, and prior respiratory or cardiovascular admission hospitalisation were predictors of poor outcome. Influenza vaccination was protective. CONCLUSION: We have developed a model that estimates the risk of respiratory hospitalisation and death in patients with COPD.
RATIONALE: A recent study showed that doctors are excessively pessimistic about the prognosis in patients with COPD and suggested that a simple tool to predict outcome is needed. METHODS: In a prospective observational study, 3343 patients with an FEV1<80% of the predicted value and FEV1/FVC<70% were selected from a clinical network of patients screened for COPD in Tayside, Scotland. Data were collected during annual visits on demography, spirometry, smoking history, medical research council (MRC) dyspnoea scale, body mass index (BMI) and other variables. The main outcome measures were hospitalisations and death secondary to COPD. A proportional hazard model was used to identify significant risk factors. RESULTS: Increasing age, low BMI, worsening MRC dyspnoea score, decreased FEV1, and prior respiratory or cardiovascular admission hospitalisation were predictors of poor outcome. Influenza vaccination was protective. CONCLUSION: We have developed a model that estimates the risk of respiratory hospitalisation and death in patients with COPD.
Authors: Bernardino Roca; Pedro Almagro; Francisco López; Francisco J Cabrera; Lorena Montero; David Morchón; Jesús Díez; Fernando de la Iglesia; Mario Fernández; Jesús Castiella; Elena Zubillaga; Jesús Recio; Joan B Soriano Journal: Intern Emerg Med Date: 2010-10-01 Impact factor: 3.397
Authors: Philip M Short; William J Anderson; Douglas H J Elder; Allan D Struthers; Brian J Lipworth Journal: Lung Date: 2015-03-29 Impact factor: 2.584
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Authors: Russell P Bowler; Victor Kim; Elizabeth Regan; André A A Williams; Stephanie A Santorico; Barry J Make; David A Lynch; John E Hokanson; George R Washko; Peter Bercz; Xavier Soler; Nathaniel Marchetti; Gerard J Criner; Joe Ramsdell; MeiLan K Han; Dawn Demeo; Antonio Anzueto; Alejandro Comellas; James D Crapo; Mark Dransfield; J Michael Wells; Craig P Hersh; Neil MacIntyre; Fernando Martinez; Hrudaya P Nath; Dennis Niewoehner; Frank Sciurba; Amir Sharafkhaneh; Edwin K Silverman; Edwin J R van Beek; Carla Wilson; Christine Wendt; Robert A Wise Journal: Chest Date: 2014-10 Impact factor: 9.410