Literature DB >> 19513798

Joint preservation after extensive curettage of knee giant cell tumors.

Miguel A Ayerza1, Luis A Aponte-Tinao, German L Farfalli, Carlos A Lores Restrepo, D Luis Muscolo.   

Abstract

UNLABELLED: Curettage is the most attractive procedure for surgically treating a giant cell tumor because it preserves joint function. However, since many giant cell tumors compromise subchondral bone this technique can jeopardize the articular surface with subsequent fractures or collapse. We asked whether intralesional curettage of a giant cell tumor close to the knee that combined morselized bone and cortical structural allograft would preserve joint function. We retrospectively reviewed 22 patients treated with that approach. The minimum followup was 2 years (average, 48 months; range, 24-80 months). The distal femur was involved in 12 patients and proximal tibia in 10. Complications and failures were recorded and functional results evaluated with Musculoskeletal Tumor Society score. We determined survivorship using the Kaplan-Meier technique using removal of the implant as the endpoint. The survival was 85% and the average functional score 28 points. Three of the 22 patients had a local tumor recurrence and one had a partial subchondral collapse not requiring further treatment. Among the remaining patients, none had fracture, infection, or knee instability. The combination of fragmented and cortical allograft allows reconstructing the bone defect and ligaments created after extensive curettage of a knee giant cell tumor obtaining normal joint function and a high survival rate with minimal complications in a high percentage of the patients. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.

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Year:  2009        PMID: 19513798      PMCID: PMC2758983          DOI: 10.1007/s11999-009-0913-8

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  22 in total

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Journal:  J Bone Joint Surg Am       Date:  1986-02       Impact factor: 5.284

2.  Intralesional excision compared with en bloc resection for giant-cell tumors of bone.

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Journal:  J Bone Joint Surg Am       Date:  1993-11       Impact factor: 5.284

3.  Giant cell tumor of long bone: a Canadian Sarcoma Group study.

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Journal:  Clin Orthop Relat Res       Date:  2002-04       Impact factor: 4.176

4.  Giant-cell tumor of bone: analysis of two hundred and eight cases in Chinese patients.

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Journal:  J Bone Joint Surg Am       Date:  1982-06       Impact factor: 5.284

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Authors:  J J Eckardt; T J Grogan
Journal:  Clin Orthop Relat Res       Date:  1986-03       Impact factor: 4.176

6.  Favourable results of acrylic cementation for giant cell tumors.

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Journal:  J Bone Joint Surg Am       Date:  1987-01       Impact factor: 5.284

8.  Knee reconstruction with preservation of the meniscus in tibial giant cell tumor.

Authors:  Jian-Min Li; Zhi-Ping Yang; Zhen-Feng Li; Xin Li; Simon R Carter
Journal:  Clin Orthop Relat Res       Date:  2008-10-02       Impact factor: 4.176

9.  A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system.

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Journal:  Clin Orthop Relat Res       Date:  1993-01       Impact factor: 4.176

10.  Giant-cell tumour of bone. The long-term results of treatment by curettage and bone graft.

Authors:  W Zhen; H Yaotian; L Songjian; L Ge; W Qingliang
Journal:  J Bone Joint Surg Br       Date:  2004-03
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  15 in total

1.  Structural allograft reconstruction of the foot and ankle after tumor resections.

Authors:  M A Ayerza; N S Piuzzi; L A Aponte-Tinao; G L Farfalli; D L Muscolo
Journal:  Musculoskelet Surg       Date:  2016-06-20

2.  Is Navigation-guided En Bloc Resection Advantageous Compared With Intralesional Curettage for Locally Aggressive Bone Tumors?

Authors:  Germán L Farfalli; Jose I Albergo; Nicolas S Piuzzi; Miguel A Ayerza; D Luis Muscolo; Lucas E Ritacco; Luis A Aponte-Tinao
Journal:  Clin Orthop Relat Res       Date:  2018-03       Impact factor: 4.176

3.  Pain and fracture after anterior cruciate ligament reconstruction caused by giant cell tumour of the distal femur.

Authors:  Daniel Dowen; Rahul Kakkar; Petra Dildey; Craig Gerrand
Journal:  BMJ Case Rep       Date:  2013-09-26

4.  What role for radiobiphosphonates bone scintigraphy in the monitoring of an unusual bone giant cell tumor: a case report and literature review.

Authors:  Salah Nabih Oueriagli; Imad Ghfir; Hassna El Guerrouj; Nouzha Ben Raïs
Journal:  Am J Nucl Med Mol Imaging       Date:  2016-04-24

5.  Oncology and functional prognosis are both vital in the surgical treatment of RGCTs around the knee joint.

Authors:  Qing Liu; Hongbo He; Yuhao Yuan; Hao Zeng; Yupeng Liu; Can Zhang; Wei Luo
Journal:  Am J Transl Res       Date:  2020-03-15       Impact factor: 4.060

6.  'Umbrella construct' - an innovative technique for reconstruction of the proximal humerus after curettage in locally aggressive benign bone tumours.

Authors:  Ashish Gulia; Ajay Puri; Srinath Gupta; Vineet Kurisunkal
Journal:  Shoulder Elbow       Date:  2020-01-10

7.  Primary total knee arthroplasty twenty years after distal femoral cement augmentation of a giant cell tumor.

Authors:  Alejandro Zylberberg; Gillian Bayley; Luca Gala; Paul R Kim
Journal:  Case Rep Orthop       Date:  2015-04-07

8.  Surgical Treatment Options for Giant Cell Tumors of Bone Around the Knee Joint: Extended Curettage or Segmental Resection?

Authors:  Hongbo He; Hao Zeng; Wei Luo; Yupeng Liu; Can Zhang; Qing Liu
Journal:  Front Oncol       Date:  2019-09-24       Impact factor: 6.244

9.  Does Osteoarticular Allograft Reconstruction Achieve Long-term Survivorship after En Bloc Resection of Grade 3 Giant Cell Tumor of Bone?

Authors:  Jose I Albergo; German L Farfalli; Angeles Cabas-Geat; Pablo Roitman; Miguel A Ayerza; Luis A Aponte-Tinao
Journal:  Clin Orthop Relat Res       Date:  2020-11       Impact factor: 4.755

Review 10.  The Great Need of a Biomechanical-Based Approach for Surgical Methods of Giant Cell Tumor: A Critical Review.

Authors:  Azadeh Ghouchani; Gholamreza Rouhi
Journal:  J Med Biol Eng       Date:  2017-06-22       Impact factor: 1.553

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