| Literature DB >> 19513644 |
John Simms1, Nathan E Hall, Polo H C Lam, Laurence J Miller, Arthur Christopoulos, Ruben Abagyan, Patrick M Sexton.
Abstract
Over 1,000 sequences likely to encode G protein-coupled receptors (GPCRs) are currently available in publicly accessible and proprietary databases and this number may grow with the refinement of a number of different genomes. However, despite recent efforts in the crystallization of these proteins, homology modeling approaches are becoming widely used as a method for obtaining quantitative and qualitative information for structure-based drug design as well as the interpretation of experimental data.Mesh：
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Year: 2009 PMID： 19513644 DOI： 10.1007/978-1-60327-317-6_7
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745