Literature DB >> 19508466

Annular leucocytoclastic vasculitis.

H Imanishi1, D Tsuruta, M Ishii, H Kobayashi.   

Abstract

Leucocytoclastic vasculitis (LV) is characterized by necrotizing inflammation around small blood vessels, composed mainly of neutrophils and their debris. The skin lesions of LV are polymorphous, but an annular variant is rare. Four previous reports have named this variant 'annular LV' (ALV) and in this paper, we report two additional cases. Patient 1 was a 80-year-old man, who presented with pruritic, erythematous target lesions on his legs, soles, abdomen and axillae; histological examination showed typical LV throughout the entire dermis. Oral prednisolone 15 mg daily rapidly resolved the patient's symptoms. Patient 2 was a 64-year-old man, who was referred to our hospital because of multiple purpuric target lesions on the buttocks, right thigh, lower legs, upper arms and forearms. Histopathology revealed LV throughout the entire dermis. Oral prednisolone 20 mg daily rapidly resolved the lesions. We categorized these cases morphologically as ALV and clinically as small-vessel vasculitis. ALV is not a distinct condition, but includes a broad range of small-vessel vasculitides.

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Year:  2009        PMID: 19508466     DOI: 10.1111/j.1365-2230.2008.03163.x

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  1 in total

1.  Annular leukocytoclastic vasculitis associated with anti-tuberculosis medications: a case report.

Authors:  Kumutnart Chanprapaph; Wanjarus Roongpisuthipong; Kunlawat Thadanipon
Journal:  J Med Case Rep       Date:  2013-01-31
  1 in total

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