B Padilla-Docal1, A J Dorta-Contreras, R Bu-Coifiú Fanego. 1. Laboratorio Central de Líquido Cefalorraquídeo, Instituto Superior de Ciencias Médicas de La Habana, La Habana, Cuba. barbara.padilla@infomed.sld.cu
Abstract
INTRODUCTION: Eosinophilic meningoencephalitis due to Angiostrongylus cantonensis is an emergent infectious disease in our area. The objective of the present paper is to determine if the activation of the complement system was taken placed with the C3c production in cerebrospinal fluid. PATIENTS AND METHODS: 14 patients with an average age 4.5 years were studied. In such patients a lumbar punction was performed. C3c was quantified in serum and cerebrospinal fluid by radial immunodiffusion. RESULTS: Median cell number was 396 x 10(-6)/L with an average of 8.8% of eosinophils. Main symptoms were headache, vomiting and fever. Meningeal signs were present in 50% of the patients. C3c intrathecal synthesis occurred in 13 patients (92.8%). CONCLUSION: It was demonstrated the participation of complement system in third-stage larvae destruction in cerebrospinal fluid.
INTRODUCTION:Eosinophilic meningoencephalitis due to Angiostrongylus cantonensis is an emergent infectious disease in our area. The objective of the present paper is to determine if the activation of the complement system was taken placed with the C3c production in cerebrospinal fluid. PATIENTS AND METHODS: 14 patients with an average age 4.5 years were studied. In such patients a lumbar punction was performed. C3c was quantified in serum and cerebrospinal fluid by radial immunodiffusion. RESULTS: Median cell number was 396 x 10(-6)/L with an average of 8.8% of eosinophils. Main symptoms were headache, vomiting and fever. Meningeal signs were present in 50% of the patients. C3c intrathecal synthesis occurred in 13 patients (92.8%). CONCLUSION: It was demonstrated the participation of complement system in third-stage larvae destruction in cerebrospinal fluid.
Authors: Bárbara Padilla-Docal; Alberto J Dorta-Contreras; Juan M Moreira; Luiggi Martini-Robles; Jenny Muzzio-Aroca; Fernando Alarcón; María Esther Magraner-Tarrau; Raisa Bu-Coifiu-Fanego Journal: Am J Trop Med Hyg Date: 2011-03 Impact factor: 2.345
Authors: Bárbara Padilla-Docal; Alberto Juan Dorta-Contreras; Raisa Bu-Coifiu-Fanego; Alexis Rodríguez-Rey; Juan Carlos Gutiérrez-Hernández; Susana Olga de Paula-Almeida Journal: Am J Trop Med Hyg Date: 2010-06 Impact factor: 2.345
Authors: Barbara Padilla-Docal; Ivonne Iglesias-González; Raisa Bu-Coifiu-Fanego; Carmen Aleida Socarrás-Hernández; Alberto Juan Dorta-Contreras Journal: Am J Trop Med Hyg Date: 2013-02 Impact factor: 2.345
Authors: Bárbara Padilla-Docal; Alberto J Dorta-Contreras; Raisa Bu-Coifiu-Fanego; René H Martínez-Alderete; Olga Susana de Paula-Almeida; Hansotto Reiber; Jens Christian Jensenius Journal: J Med Case Rep Date: 2011-07-28
Authors: Barbara Padilla-Docal; Alberto J Dorta-Contreras; Raisa Bu-Coifiu-Fanego; Alexis Rodriguez Rey Journal: Cerebrospinal Fluid Res Date: 2009-07-02