Literature DB >> 19505824

Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.

Josep Bonjoch1, Faïza Diaba, Lluís Pagès, Daniel Pérez, Lidia Soca, Montserrat Miralpeix, Dolors Vilella, Paquita Anton, Carles Puig.   

Abstract

A gamma-carboline series of cysLT(1) receptor antagonists has been prepared. Some of the compounds show good potencies both, in vitro and in vivo, compared to the standard compounds.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19505824     DOI： 10.1016/j.bmcl.2009.05.094

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands.

Authors:  Haitao You; Vinicius M Gadotti; Ravil R Petrov; Gerald W Zamponi; Philippe Diaz
Journal:  Mol Pain       Date:  2011-11-17       Impact factor: 3.395

2.  Mild and efficient Winterfeldt oxidation of 1,2,3,4-tetrahydro-γ-carbolines for the synthesis of dihydropyrrolo[3,2-b]-quinolones and pyrrolo[3,2-b]quinolones.

Authors:  Rong Sheng; Jiangwei Zhu; Yongzhou Hu
Journal:  Molecules       Date:  2012-01-30       Impact factor: 4.411
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.