Ultrastructure of the guinea pig cochlear aqueduct. An electron microscopic study of decalcified temporal bones.

The ultrastructure of the guinea pig cochlear aqueduct was examined using semi-thin and thin sections. The lumen of the cochlear aqueduct was occupied by a sparse meshwork of fibroblasts and delicate connective tissue trabeculae. The periotic tissue lining the bony wall of the aqueduct was composed of multiple layers of both elongated cells and densely arranged laminae of collagen fibrils. These structures were identical to those of the dura mater and the arachnoid. The opening to the perilymphatic space of the scala tympani also contained connective tissue trabeculae, but the arrangement of fibroblasts was more compact here than in the main part of the duct. These structural features suggest that fluid can move freely through cochlear aqueduct, and that the effects of sudden pressure changes in the CSF may be protected against by the densely and perpendicularly arranged fibroblast at the opening to the perilymphatic space.