Literature DB >> 19504349

Black hip, fracture neck of femur and scoliosis: a case of ochronosis.

B Zacharia1, J Chundarathil, V Ramakrishnan, R M Krishnankutty, R Veluthedath, K Puthezhath, I Varughese.   

Abstract

BACKGROUND: Ochronosis is a very rare disorder with an incidence of 2 to 5 per million live births. It is a genetic disorder with autosomal recessive inheritance. It is characterized by dark brown pigmentation of cartilage, capsules of joints and other soft tissues. Ochronosis usually presents as ochronotic arthropathy and spondylosis.
PURPOSE: This article describes a very rare presentation of scoliosis and fracture of the neck of the femur in a patient with ochronosis.
METHODS: A 65-year-old woman with left-sided scoliosis presented to us following a fall with fracture of the neck of the femur on the left side. Radiological examination and biochemical study of urine were consistent with ochronosis. PROCEDURE AND
RESULTS: We have treated the patient by excision arthroplasty.
CONCLUSION: We report a case of scoliosis, fracture of the neck of the femur and ochronosis occurring together in a patient.

Entities:  

Mesh:

Year:  2009        PMID: 19504349     DOI: 10.1007/s10545-009-1172-2

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN: 0141-8955            Impact factor:   4.982


  30 in total

Review 1.  The pathology of alkaptonuric ochronosis.

Authors:  J J Gaines
Journal:  Hum Pathol       Date:  1989-01       Impact factor: 3.466

2.  Ochronotic arthritis.

Authors:  V M Soodan
Journal:  J Indian Med Assoc       Date:  1976-03-16

3.  Ochronosis and alkaptonuria: report of a new case with calcified aortic valve stenosis.

Authors:  L Dereymaeker; G Van Parijs; M Bayart; W Daenen; J Lauwerijns; H De Geest
Journal:  Acta Cardiol       Date:  1990       Impact factor: 1.718

4.  [Simultaneous occurrence of gout and ochronosis].

Authors:  D Szántó
Journal:  Fortschr Geb Rontgenstr Nuklearmed       Date:  1968-10

5.  Palmoplantar pigmentation: a clue to alkaptonuric ochronosis.

Authors:  S Cherian
Journal:  J Am Acad Dermatol       Date:  1994-02       Impact factor: 11.527

6.  [Alkaptonuria: a rare cause of urine discoloration. Report of a case in a newborn].

Authors:  L Adonis-Koffy; E Gonzalès; S Nathanson; C Spodek; A Bensman
Journal:  Arch Pediatr       Date:  2000-08       Impact factor: 1.180

7.  Bone metabolism in ochronotic patients.

Authors:  G Aliberti; I Pulignano; A Schiappoli; S Minisola; E Romagnoli; M Proietta
Journal:  J Intern Med       Date:  2003-09       Impact factor: 8.989

8.  [Biomechanical studies on the pathogenesis of ochronotic arthropathy].

Authors:  P Eberle; W Mohr; L Claes
Journal:  Z Rheumatol       Date:  1984 Sep-Oct       Impact factor: 1.372

Review 9.  Alkaptonuria and renal failure: a case report and review of the literature.

Authors:  V S Venkataseshan; B Chandra; V Graziano; P Steinlauf; E Marquet; V Irmiere; M A Needle
Journal:  Mod Pathol       Date:  1992-07       Impact factor: 7.842

10.  Ocular ochronosis from alkaptonuria.

Authors:  D M Carlson; M K Helgeson; J A Hiett
Journal:  J Am Optom Assoc       Date:  1991-11
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  4 in total

1.  Alkaptonuric arthropathy with periprosthetic fracture:a case report.

Authors:  S Durgaprasad Hegde; Siva Ranjan D; Muralidhar B M; Epari Sanjeeva Rao; P S B Hussain
Journal:  J Clin Diagn Res       Date:  2014-03-15

2.  Treatment of osteoporotic fractures in alkaptonuria by teriparatide stimulates bone formation and decreases fracture rate - A report of two cases.

Authors:  L R Ranganath; M Khedr; A Mistry; S Vinjamuri; J A Gallagher
Journal:  Bone Rep       Date:  2021-11-28

3.  Ochronotic Arthropathy: Two Case Reports from a Developing Country.

Authors:  Farooq A Rathore; Saeed B Ayaz; Sahibzada N Mansoor
Journal:  Clin Med Insights Arthritis Musculoskelet Disord       Date:  2016-02-09

Review 4.  Musculoskeletal manifestations of alkaptonuria: A case report and literature review.

Authors:  Katherine Wu; Erin Bauer; Gihyun Myung; Meika A Fang
Journal:  Eur J Rheumatol       Date:  2018-11-16
  4 in total

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