Literature DB >> 19504084

Hyperglycaemia and hyperinsulinaemia: is insulin-degrading enzyme the missing link?

J Fawcett1, W C Duckworth.   

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Year:  2009        PMID： 19504084     DOI： 10.1007/s00125-009-1414-8

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  31 in total

1.  Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes.

Authors:  F G Hamel; R G Bennett; J L Upward; W C Duckworth
Journal:  Endocrinology       Date:  2001-06       Impact factor: 4.736

2.  Metalloendoprotease inhibitors which block the differentiation of L6 myoblasts inhibit insulin degradation by the endogenous insulin-degrading enzyme.

Authors:  C Kayalar; W T Wong
Journal:  J Biol Chem       Date:  1989-05-25       Impact factor: 5.157

3.  Effects of metalloendoprotease inhibitors on insulin binding, internalization and processing in adipocytes.

Authors:  A Jochen; P Berhanu
Journal:  Biochem Biophys Res Commun       Date:  1987-01-15       Impact factor: 3.575

4.  Degradation of intraendosomal insulin by insulin-degrading enzyme without acidification.

Authors:  F G Hamel; M J Mahoney; W C Duckworth
Journal:  Diabetes       Date:  1991-04       Impact factor: 9.461

5.  Insulin acts intracellularly on proteasomes through insulin-degrading enzyme.

Authors:  W C Duckworth; R G Bennett; F G Hamel
Journal:  Biochem Biophys Res Commun       Date:  1998-03-17       Impact factor: 3.575

Review 6.  The functional significance of Shc in insulin signaling as a substrate of the insulin receptor.

Authors:  T Sasaoka; M Kobayashi
Journal:  Endocr J       Date:  2000-08       Impact factor: 2.349

7.  Insulin-degrading enzyme: stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes.

Authors:  J A Affholter; C L Hsieh; U Francke; R A Roth
Journal:  Mol Endocrinol       Date:  1990-08

8.  Insulin inhibition of the proteasome is dependent on degradation of insulin by insulin-degrading enzyme.

Authors:  R G Bennett; J Fawcett; M C Kruer; W C Duckworth; F G Hamel
Journal:  J Endocrinol       Date:  2003-06       Impact factor: 4.286

9.  Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

Authors:  Samer Karamohamed; Serkalem Demissie; Jeannine Volcjak; Chunyu Liu; Nancy Heard-Costa; Jun Liu; Christina M Shoemaker; Carolien I Panhuysen; James B Meigs; Peter Wilson; Larry D Atwood; L Adrienne Cupples; Alan Herbert
Journal:  Diabetes       Date:  2003-06       Impact factor: 9.461

10.  Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.

Authors:  Wesley Farris; Stefan Mansourian; Yang Chang; Loren Lindsley; Elizabeth A Eckman; Matthew P Frosch; Christopher B Eckman; Rudolph E Tanzi; Dennis J Selkoe; Suzanne Guenette
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-12       Impact factor: 11.205
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  3 in total

1.  Effect of dexamethasone and testosterone treatment on the regulation of insulin-degrading enzyme and cellular changes in ventral rat prostate after castration.

Authors:  Juliany S B César Vieira; Karina L A Saraiva; Maria C L Barbosa; Regina C C Porto; Juan C Cresto; Christina A Peixoto; Maria I Wanderley; Daniel P Udrisar
Journal:  Int J Exp Pathol       Date:  2011-04-21       Impact factor: 1.925

2.  Insulin-degrading enzyme binds to the nonglycosylated precursor of varicella-zoster virus gE protein found in the endoplasmic reticulum.

Authors:  J E Carpenter; W Jackson; G A de Souza; L Haarr; C Grose
Journal:  J Virol       Date:  2009-10-28       Impact factor: 5.103

3.  Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis.

Authors:  Julie Charton; Marion Gauriot; Qing Guo; Nathalie Hennuyer; Xavier Marechal; Julie Dumont; Malika Hamdane; Virginie Pottiez; Valerie Landry; Olivier Sperandio; Marion Flipo; Luc Buee; Bart Staels; Florence Leroux; Wei-Jen Tang; Benoit Deprez; Rebecca Deprez-Poulain
Journal:  Eur J Med Chem       Date:  2014-04-04       Impact factor: 6.514
  3 in total

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