| Literature DB >> 19503920 |
Wesleigh F Edwards1, Douglas D Young, Alexander Deiters.
Abstract
The effect of microwave irradiation on DNA/DNA hybridization has been studied under controlled power and temperature conditions. It was discovered that microwave irradiation led to the melting of double-stranded deoxyoligonucleotides well below their thermal melting temperature and independent of the length of the deoxyoligonucleotides. These observations indicate a specific interaction of microwaves with DNA, and have important implications in the chemical or enzymatic processing of DNA under microwave heating.Mesh:
Substances:
Year: 2009 PMID: 19503920 DOI: 10.1039/b903609a
Source DB: PubMed Journal: Org Biomol Chem ISSN: 1477-0520 Impact factor: 3.876