Literature DB >> 19503086

betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses.

Geeske M van Woerden1, Freek E Hoebeek, Zhenyu Gao, Raghavendra Y Nagaraja, Casper C Hoogenraad, Steven A Kushner, Christian Hansel, Chris I De Zeeuw, Ype Elgersma.   

Abstract

We found that betaCaMKII, the predominant CaMKII isoform of the cerebellum, is important for controlling the direction of plasticity at the parallel fiber-Purkinje cell synapse; a protocol that induced synaptic depression in wild-type mice resulted in synaptic potentiation in Camk2b knockout mice and vice versa. These findings provide us with unique experimental insight into the mechanisms that transduce graded calcium signals into either synaptic depression or potentiation.

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Year:  2009        PMID： 19503086     DOI： 10.1038/nn.2329

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


  15 in total

1.  A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP.

Authors:  Varda Lev-Ram; Scott T Wong; Daniel R Storm; Roger Y Tsien
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-04       Impact factor: 11.205

2.  Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning.

Authors:  Ype Elgersma; Nikolai B Fedorov; Sami Ikonen; Esther S Choi; Minetta Elgersma; Ofelia M Carvalho; Karl Peter Giese; Alcino J Silva
Journal:  Neuron       Date:  2002-10-24       Impact factor: 17.173

3.  alpha- and betaCaMKII. Inverse regulation by neuronal activity and opposing effects on synaptic strength.

Authors:  Tara C Thiagarajan; Erika S Piedras-Renteria; Richard W Tsien
Journal:  Neuron       Date:  2002-12-19       Impact factor: 17.173

4.  Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.

Authors:  A J Silva; C F Stevens; S Tonegawa; Y Wang
Journal:  Science       Date:  1992-07-10       Impact factor: 47.728

5.  alphaCaMKII Is essential for cerebellar LTD and motor learning.

Authors:  Christian Hansel; Marcel de Jeu; Amor Belmeguenai; Simone H Houtman; Gabriëlle H S Buitendijk; Dmitri Andreev; Chris I De Zeeuw; Ype Elgersma
Journal:  Neuron       Date:  2006-09-21       Impact factor: 17.173

6.  A role for protein phosphatases 1, 2A, and 2B in cerebellar long-term potentiation.

Authors:  Amor Belmeguenai; Christian Hansel
Journal:  J Neurosci       Date:  2005-11-16       Impact factor: 6.167

7.  The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure.

Authors:  Ken-Ichi Okamoto; Radhakrishnan Narayanan; Sang H Lee; Kazuyoshi Murata; Yasunori Hayashi
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-02       Impact factor: 11.205

8.  Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning.

Authors:  K P Giese; N B Fedorov; R K Filipkowski; A J Silva
Journal:  Science       Date:  1998-02-06       Impact factor: 47.728

9.  Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation.

Authors:  K Shen; T Meyer
Journal:  Science       Date:  1999-04-02       Impact factor: 47.728

10.  Ca2+ requirements for cerebellar long-term synaptic depression: role for a postsynaptic leaky integrator.

Authors:  Keiko Tanaka; Leonard Khiroug; Fidel Santamaria; Tomokazu Doi; Hideaki Ogasawara; Graham C R Ellis-Davies; Mitsuo Kawato; George J Augustine
Journal:  Neuron       Date:  2007-06-07       Impact factor: 17.173
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  56 in total

1.  Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases.

Authors:  Kathryn B Grey; Brian D Burrell
Journal:  J Neurophysiol       Date:  2010-03-24       Impact factor: 2.714

2.  A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice.

Authors:  Thomas J Hund; Olha M Koval; Jingdong Li; Patrick J Wright; Lan Qian; Jedidiah S Snyder; Hjalti Gudmundsson; Crystal F Kline; Nathan P Davidson; Natalia Cardona; Matthew N Rasband; Mark E Anderson; Peter J Mohler
Journal:  J Clin Invest       Date:  2010-09-27       Impact factor: 14.808

3.  Distinct kinetics of synaptic structural plasticity, memory formation, and memory decay in massed and spaced learning.

Authors:  Wajeeha Aziz; Wen Wang; Sebnem Kesaf; Alsayed Abdelhamid Mohamed; Yugo Fukazawa; Ryuichi Shigemoto
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-23       Impact factor: 11.205

Review 4.  Distributed synergistic plasticity and cerebellar learning.

Authors:  Zhenyu Gao; Boeke J van Beugen; Chris I De Zeeuw
Journal:  Nat Rev Neurosci       Date:  2012-08-16       Impact factor: 34.870

5.  Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors.

Authors:  Izuki Amano; Yusuke Takatsuru; Syutaro Toya; Asahi Haijima; Toshiharu Iwasaki; Helmut Grasberger; Samuel Refetoff; Noriyuki Koibuchi
Journal:  Thyroid       Date:  2016-03-23       Impact factor: 6.568

6.  Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses.

Authors:  Xin Guan; Yanhong Duan; Qingwen Zeng; Hongjie Pan; Yu Qian; Dali Li; Xiaohua Cao; Mingyao Liu
Journal:  J Biol Chem       Date:  2014-07-25       Impact factor: 5.157

Review 7.  Spatiotemporal firing patterns in the cerebellum.

Authors:  Chris I De Zeeuw; Freek E Hoebeek; Laurens W J Bosman; Martijn Schonewille; Laurens Witter; Sebastiaan K Koekkoek
Journal:  Nat Rev Neurosci       Date:  2011-05-05       Impact factor: 34.870

8.  CaMKII: the Swiss army knife of synaptic plasticity.

Authors:  Karam Kim; Yasunori Hayashi
Journal:  J Physiol       Date:  2014-11-15       Impact factor: 5.182

9.  The gamma isoform of CaM kinase II controls mouse egg activation by regulating cell cycle resumption.

Authors:  Johannes Backs; Paula Stein; Thea Backs; Francesca E Duncan; Chad E Grueter; John McAnally; Xiaoxia Qi; Richard M Schultz; Eric N Olson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-04       Impact factor: 11.205

Review 10.  Actin in dendritic spines: connecting dynamics to function.

Authors:  Pirta Hotulainen; Casper C Hoogenraad
Journal:  J Cell Biol       Date:  2010-05-10       Impact factor: 10.539
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