Literature DB >> 19502816

(micro)Genomic medicine: microRNAs as therapeutics and biomarkers.

Matthew A Saunders1, Lee P Lim.   

Abstract

Genomic studies have shown that a microRNA(miRNA) can post-transcriptionally regulate hundreds of other genes, providing challenges and opportunities for therapeutic development. Profiling studies have placed several miRNAs within transcriptional pathways linked to disease, and oligonucleotide therapeutics are being developed that modulate miRNA activity. The involvement of miRNAs in diverse genetic pathways across human tissues suggests that miRNAs will also be useful as biomarkers for disease and tissue injury.

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Year:  2009        PMID： 19502816     DOI： 10.4161/rna.6.3.8871

Source DB:  PubMed          Journal:  RNA Biol        ISSN： 1547-6286            Impact factor:   4.652


  10 in total

Review 1.  Genome-wide approaches in the study of microRNA biology.

Authors:  Melissa L Wilbert; Gene W Yeo
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2010-12-31

2.  Research in the exercise sciences: where we are and where do we go from here--Part II.

Authors:  Kenneth M Baldwin; Fadia Haddad
Journal:  Exerc Sport Sci Rev       Date:  2010-04       Impact factor: 6.230

3.  LNA Inhibitor in microRNA miR-23b as a Potential Anti-proliferative Option in Human Hepatocellular Carcinoma.

Authors:  Zoya Najafi; Mohammadreza Sharifi; Gholamreza Javadi
Journal:  J Gastrointest Cancer       Date:  2020-03

4.  Degradation of miR-21 induces apoptosis and inhibits cell proliferation in human hepatocellular carcinoma.

Authors:  Z Najafi; M Sharifi; G Javadi
Journal:  Cancer Gene Ther       Date:  2015-10-02       Impact factor: 5.987

5.  MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer.

Authors:  Shahana Majid; Sharanjot Saini; Altaf A Dar; Hiroshi Hirata; Varahram Shahryari; Yuichiro Tanaka; Soichiro Yamamura; Koji Ueno; Mohd Saif Zaman; Kamaldeep Singh; Inik Chang; Guoren Deng; Rajvir Dahiya
Journal:  Cancer Res       Date:  2011-02-17       Impact factor: 12.701

6.  Inhibition of microRNA miR-92a induces apoptosis and inhibits cell proliferation in human acute promyelocytic leukemia through modulation of p63 expression.

Authors:  Mohammadreza Sharifi; Rasoul Salehi; Yousof Gheisari; Mohammad Kazemi
Journal:  Mol Biol Rep       Date:  2014-01-31       Impact factor: 2.316

7.  Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes.

Authors:  Robert Häsler; Gunnar Jacobs; Andreas Till; Nils Grabe; Christian Cordes; Susanna Nikolaus; Kaiqin Lao; Stefan Schreiber; Philip Rosenstiel
Journal:  PLoS One       Date:  2012-02-17       Impact factor: 3.240

8.  miR-214 promotes radioresistance in human ovarian cancer cells by targeting PETN.

Authors:  Qin Zhang; Shuxiang Zhang
Journal:  Biosci Rep       Date:  2017-07-04       Impact factor: 3.840

9.  MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer.

Authors:  Shahana Majid; Altaf A Dar; Sharanjot Saini; Guoren Deng; Inik Chang; Kirsten Greene; Yuichiro Tanaka; Rajvir Dahiya; Soichiro Yamamura
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240

Review 10.  The non-coding oncogene: a case of missing DNA evidence?

Authors:  Puja Shahrouki; Erik Larsson
Journal:  Front Genet       Date:  2012-09-12       Impact factor: 4.599
  10 in total

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