| Literature DB >> 19502752 |
Yuriko Yamaoka1, Kenji Ohguchi, Tomohiro Itoh, Yoshinori Nozawa, Yukihiro Akao.
Abstract
In this study, we examined the effects of theaflavins, polyphenols in black tea, on alpha melanocyte-stimulating hormone (alphaMSH)-induced melanogenesis in mouse B16 melanoma cells. Among theaflavins, theaflavin-3,3'-digallate (TF-3) exhibited a potent inhibitory effect on melanogenesis. Our results indicate that the inhibitory effect of TF-3 on melanogenesis is due to suppression of tyrosinase protein and mRNA levels.Entities:
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Year: 2009 PMID: 19502752 DOI: 10.1271/bbb.80880
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN: 0916-8451 Impact factor: 2.043