Literature DB >> 1949977

Antiepileptic medications in development.

N M Graves1, I E Leppik.   

Abstract

Recently, there has been an increase in the research devoted to the study of investigational antiepileptic medications. This has led to extensive clinical trials of several new compounds. This review focuses on four of these antiepileptic medications in development: felbamate, gabapentin, lamotrigine, and vigabatrin. Each has a unique mechanism of action and great potential for the treatment of epilepsy.

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Year:  1991        PMID: 1949977     DOI: 10.1177/106002809102500913

Source DB:  PubMed          Journal:  DICP        ISSN: 1042-9611


  5 in total

Review 1.  Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy.

Authors:  D H Peters; E M Sorkin
Journal:  Drugs       Date:  1993-05       Impact factor: 9.546

Review 2.  Felbamate. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy.

Authors:  Katharine J Palmer; Donna McTavish
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

Review 3.  Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy.

Authors:  Karen L Goa; Eugene M Sorkin
Journal:  Drugs       Date:  1993-09       Impact factor: 9.546

Review 4.  Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy.

Authors:  K L Goa; S R Ross; P Chrisp
Journal:  Drugs       Date:  1993-07       Impact factor: 9.546

Review 5.  Topiramate. A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy.

Authors:  H D Langtry; J C Gillis; R Davis
Journal:  Drugs       Date:  1997-11       Impact factor: 9.546

  5 in total

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