Literature DB >> 19499095

Potential microbial origins of schizophrenia and their treatments.

S Hossein Fatemi1.   

Abstract

Schizophrenia is a severe brain disease that affects approximately 1% of the world's population. Extensive study into the indication of and causes of this disease has been ongoing for decades. Historical review of research into associated abnormalities and markers common in schizophrenic patients has demonstrated a correlation with potential microbial origins in the development of the disease. While infectious etiologies could be responsible for some cases of schizophrenia, no consistent use of anti-infective agents has been developed for its prevention or treatment. Elucidation of the mechanisms for infectious roots of schizophrenia may open new avenues for effective treatment. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

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Year:  2009        PMID: 19499095      PMCID: PMC2733838          DOI: 10.1358/dot.2009.45.4.1353924

Source DB:  PubMed          Journal:  Drugs Today (Barc)        ISSN: 1699-3993            Impact factor:   2.245


  124 in total

Review 1.  Hematolymphopoietic and inflammatory cytokines in neural development.

Authors:  M F Mehler; J A Kessler
Journal:  Trends Neurosci       Date:  1997-08       Impact factor: 13.837

Review 2.  Recent advances in defining the neuropathology of schizophrenia.

Authors:  S E Arnold; J Q Trojanowski
Journal:  Acta Neuropathol       Date:  1996-09       Impact factor: 17.088

3.  Inflammatory cytokine (interleukins 1, 6 and 8 and tumor necrosis factor-alpha) release from cultured human fetal membranes in response to endotoxic lipopolysaccharide mirrors amniotic fluid concentrations.

Authors:  S J Fortunato; R P Menon; K F Swan; R Menon
Journal:  Am J Obstet Gynecol       Date:  1996-06       Impact factor: 8.661

Review 4.  Growth factor regulation of neuronal development.

Authors:  M F Mehler; J A Kessler
Journal:  Dev Neurosci       Date:  1994       Impact factor: 2.984

5.  Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

Authors:  S Akbarian; J J Kim; S G Potkin; J O Hagman; A Tafazzoli; W E Bunney; E G Jones
Journal:  Arch Gen Psychiatry       Date:  1995-04

6.  Excess seasonality of births among patients with schizophrenia and seasonal ovopathy.

Authors:  E G Pallast; P H Jongbloet; H M Straatman; G A Zielhuis
Journal:  Schizophr Bull       Date:  1994       Impact factor: 9.306

7.  Prenatal influenza infections and adult schizophrenia.

Authors:  S A Mednick; M O Huttunen; R A Machón
Journal:  Schizophr Bull       Date:  1994       Impact factor: 9.306

8.  Maternal influenza, obstetric complications, and schizophrenia.

Authors:  P Wright; N Takei; L Rifkin; R M Murray
Journal:  Am J Psychiatry       Date:  1995-12       Impact factor: 18.112

9.  Expression of inflammatory cytokines (interleukin-1 beta and interleukin-6) in amniochorionic membranes.

Authors:  R Menon; K F Swan; T W Lyden; N S Rote; S J Fortunato
Journal:  Am J Obstet Gynecol       Date:  1995-02       Impact factor: 8.661

Review 10.  Developmentally moderated expressions of the neuropathology underlying schizophrenia.

Authors:  E F Walker
Journal:  Schizophr Bull       Date:  1994       Impact factor: 9.306

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  1 in total

Review 1.  Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders.

Authors:  Roberta Zanardini; Miriam Ciani; Luisa Benussi; Roberta Ghidoni
Journal:  Front Aging Neurosci       Date:  2016-02-01       Impact factor: 5.750

  1 in total

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