Literature DB >> 19498666

Adaptive Scanning Optical Microscope (ASOM): A multidisciplinary optical microscope design for large field of view and high resolution imaging.

Benjamin Potsaid, Yves Bellouard, John Wen.   

Abstract

From micro-assembly to biological observation, the optical microscope remains one of the most important tools for observing below the threshold of the naked human eye. However, in its conventional form, it suffers from a trade-off between resolution and field of view. This paper presents a new optical microscope design that combines a high speed steering mirror, a custom designed scanner lens, a MEMS deformable mirror, and additional imaging optics to enlarge the field of view while preserving resolving power and operating at a high image acquisition rate. We describe the theory of operation and our design methodology, present a preliminary simulated design, and compare to existing technologies. A reduced functionality experimental prototype demonstrates both micro-assembly and biological observation tasks.

Entities:  

Year:  2005        PMID: 19498666     DOI: 10.1364/opex.13.006504

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  9 in total

1.  Closed loop adaptive optics for microscopy without a wavefront sensor.

Authors:  Peter Kner; Lukman Winoto; David A Agard; John W Sedat
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2010-02-24

2.  Review of bio-optical imaging systems with a high space-bandwidth product.

Authors:  Jongchan Park; David J Brady; Guoan Zheng; Lei Tian; Liang Gao
Journal:  Adv Photonics       Date:  2021-06-26

3.  High-resolution wide-field microscopy with adaptive optics for spherical aberration correction and motionless focusing.

Authors:  P Kner; J W Sedat; D A Agard; Z Kam
Journal:  J Microsc       Date:  2010-02       Impact factor: 1.758

4.  Wide field-of-view volumetric imaging by a mesoscopic scanning oblique plane microscopy with switchable objective lenses.

Authors:  Wenjun Shao; Kivilcim Kilic; Wenqing Yin; Gregory Wirak; Xiaodan Qin; Hui Feng; David Boas; Christopher V Gabel; Ji Yi
Journal:  Quant Imaging Med Surg       Date:  2021-03

5.  Fast widefield scan provides tunable and uniform illumination optimizing super-resolution microscopy on large fields.

Authors:  Adrien Mau; Karoline Friedl; Christophe Leterrier; Nicolas Bourg; Sandrine Lévêque-Fort
Journal:  Nat Commun       Date:  2021-05-24       Impact factor: 14.919

Review 6.  Something has to give: scaling combinatorial computing by biological agents exploring physical networks encoding NP-complete problems.

Authors:  Falco C M J M van Delft; Giulia Ipolitti; Dan V Nicolau; Ayyappasamy Sudalaiyadum Perumal; Ondřej Kašpar; Sara Kheireddine; Sebastian Wachsmann-Hogiu; Dan V Nicolau
Journal:  Interface Focus       Date:  2018-10-19       Impact factor: 3.906

Review 7.  Microfluidic Based Optical Microscopes on Chip.

Authors:  Petra Paiè; Rebeca Martínez Vázquez; Roberto Osellame; Francesca Bragheri; Andrea Bassi
Journal:  Cytometry A       Date:  2018-09-13       Impact factor: 4.355

8.  GANscan: continuous scanning microscopy using deep learning deblurring.

Authors:  Michael John Fanous; Gabriel Popescu
Journal:  Light Sci Appl       Date:  2022-09-07       Impact factor: 20.257

9.  Head-Mounted Display-Based Microscopic Imaging System with Customizable Field Size and Viewpoint.

Authors:  Tadayoshi Aoyama; Sarau Takeno; Masaru Takeuchi; Yasuhisa Hasegawa
Journal:  Sensors (Basel)       Date:  2020-04-01       Impact factor: 3.576

  9 in total

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