| Literature DB >> 19494075 |
David C Alexander1, Jennifer L Guthrie, Daria Pyskir, Anne Maki, Natalia Kurepina, Barry N Kreiswirth, Pamela Chedore, Steven J Drews, Frances Jamieson.
Abstract
A collection of 1,308 clinical Mycobacterium tuberculosis isolates from Ontario, Canada, was genotyped by IS6110 restriction fragment length polymorphism (RFLP) and mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) analysis. RFLP or >12 MIRU-VNTR loci were necessary for resolution of Indo-Oceanic strains. The low clustering rate and high strain diversity indicate that, in Ontario, most tuberculosis results from reactivation of latent infections.Entities:
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Year: 2009 PMID: 19494075 PMCID: PMC2725669 DOI: 10.1128/JCM.01946-08
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948