| Literature DB >> 19494065 |
Anandi Martin1, Peter Munga Waweru, Fred Babu Okatch, Naureen Amondi Ouma, Laurence Bonte, Francis Varaine, Françoise Portaels.
Abstract
The objective of this study was to evaluate the performance of a low-cost method, the thin layer agar (TLA) method, for the diagnosis of smear-negative patients. This prospective study was performed in Homa Bay District Hospital in Kenya. Out of 1,584 smear-negative sputum samples, 212 (13.5%) were positive by culture in Löwenstein-Jensen medium (LJ) and 220 (14%) were positive by the TLA method. The sensitivities of LJ and TLA were 71% and 74%, respectively. TLA could become an affordable method for the diagnosis of smear-negative tuberculosis in resource-limited settings, with results available within 2 weeks.Entities:
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Year: 2009 PMID: 19494065 PMCID: PMC2725698 DOI: 10.1128/JCM.00264-09
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948