Literature DB >> 19493531

Particle deposition in a CT-scanned human lung airway.

H Y Luo1, Y Liu.   

Abstract

The particle deposition in a computerized tomography (CT)-scanned human lung was numerically investigated. The five-generation airway is extracted from the trachea to segmental bronchi of a 60-year-old Chinese male patient. Computations were carried out in the flow rate range of 210-630 ml/s (Reynolds number range of 1000-3000) and particle size of 2-10 microm (Stokes number range of 0.0007-0.049). To count the effect of laryngeal jet on trachea inlet, the trachea was extended and modified to simulate the larynx, consequently the inlet velocity profile is biased towards the rear wall. The laryngeal jet-induced turbulence was simulated using low Reynolds number (LRN) kappa-omega turbulent model. Particle deposition patterns, deposition efficiency and deposition factor were studied in detail. The turbulent flow has significant effect on the particle deposition, and the present deposition factor is compared well with the available data.

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Year:  2009        PMID: 19493531     DOI: 10.1016/j.jbiomech.2009.05.004

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  6 in total

1.  Fluid flow and particle transport in mechanically ventilated airways. Part II: particle transport.

Authors:  Mohammed Alzahrany; Timothy Van Rhein; Arindam Banerjee; Gary Salzman
Journal:  Med Biol Eng Comput       Date:  2015-11-05       Impact factor: 2.602

2.  A multiscale MDCT image-based breathing lung model with time-varying regional ventilation.

Authors:  Youbing Yin; Jiwoong Choi; Eric A Hoffman; Merryn H Tawhai; Ching-Long Lin
Journal:  J Comput Phys       Date:  2013-07-01       Impact factor: 3.553

3.  Inter-species Variabilities of Droplet Transport, Size Change, and Deposition in Human and Rat Respiratory Systems: An In Silico Study.

Authors:  Hamideh Hayati; Yu Feng; Myron Hinsdale
Journal:  J Aerosol Sci       Date:  2021-01-23       Impact factor: 3.433

4.  Patient-specific modeling of aerosol delivery in healthy and asthmatic adults.

Authors:  Kamran Poorbahrami; David G Mummy; Sean B Fain; Jessica M Oakes
Journal:  J Appl Physiol (1985)       Date:  2019-09-12

5.  Particle Disposition in the Realistic Airway Tree Models of Subjects with Tracheal Bronchus and COPD.

Authors:  Baihua Zhang; Shouliang Qi; Yong Yue; Jing Shen; Chen Li; Wei Qian; Jianlin Wu
Journal:  Biomed Res Int       Date:  2018-08-05       Impact factor: 3.411

6.  Targeting inhaled aerosol delivery to upper airways in children: Insight from computational fluid dynamics (CFD).

Authors:  Prashant Das; Eliram Nof; Israel Amirav; Stavros C Kassinos; Josué Sznitman
Journal:  PLoS One       Date:  2018-11-20       Impact factor: 3.240

  6 in total

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