Literature DB >> 1949153

Helix-loop-helix genes translocated in lymphoid leukemia.

J Visvader1, C G Begley.   

Abstract

A new class of DNA-binding proteins with a helix-loop-helix (HLH) structure has recently been described. Many of these transcriptional regulators are known to play a central role in cell-specification and differentiation processes. Four members of the HLH family are now implicated in the development of human lymphoid malignancies as a result of aberrant expression following chromosomal translocation events. This review focuses on two of these family members: SCL and LYL-1.

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Year:  1991        PMID： 1949153     DOI： 10.1016/0968-0004(91)90137-k

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  16 in total

1.  Localization of murine HLH gene NSCL to chromosome 1 by use of recombinant inbred strains.

Authors:  N M Gough; S Lipkowitz; I R Kirsch; C G Begley
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Molecular cloning of the chicken SCL cDNA.

Authors:  G Goodwin; A MacGregor; J Zhu; M R Crompton
Journal:  Nucleic Acids Res       Date:  1992-01-25       Impact factor: 16.971

3.  Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system.

Authors:  C G Begley; S Lipkowitz; V Göbel; K A Mahon; V Bertness; A R Green; N M Gough; I R Kirsch
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

4.  The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.

Authors:  A Krapp; M Knöfler; S Frutiger; G J Hughes; O Hagenbüchle; P K Wellauer
Journal:  EMBO J       Date:  1996-08-15       Impact factor: 11.598

5.  Induction of basic helix-loop-helix protein-containing complexes during erythroid differentiation.

Authors:  J A Lister; M H Baron
Journal:  Gene Expr       Date:  1998

6.  Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer.

Authors:  V Fernández-Majada; C Aguilera; A Villanueva; F Vilardell; A Robert-Moreno; A Aytés; F X Real; G Capella; M W Mayo; L Espinosa; A Bigas
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-26       Impact factor: 11.205

7.  Exon skipping due to a mutation in a donor splice site in the WT-1 gene is associated with Wilms' tumor and severe genital malformations.

Authors:  S Schneider; G Wildhardt; R Ludwig; B Royer-Pokora
Journal:  Hum Genet       Date:  1993-07       Impact factor: 4.132

8.  The SCL gene product is regulated by and differentially regulates cytokine responses during myeloid leukemic cell differentiation.

Authors:  T Tanigawa; N Elwood; D Metcalf; D Cary; E DeLuca; N A Nicola; C G Begley
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

9.  Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system.

Authors:  S M Hollenberg; R Sternglanz; P F Cheng; H Weintraub
Journal:  Mol Cell Biol       Date:  1995-07       Impact factor: 4.272

10.  ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development.

Authors:  M Lopez; P Oettgen; Y Akbarali; U Dendorfer; T A Libermann
Journal:  Mol Cell Biol       Date:  1994-05       Impact factor: 4.272
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