| Literature DB >> 19491039 |
Abstract
Thanks to new evidence we are now a step closer to understanding how neurons produce amyloid-beta peptide (Abeta)-the chief culprit of Alzheimer's disease. As importance of clathrin-mediated endocytosis to normal neurons has become clearer, so has its role in pathology of neurological disorders. Here we update recent evidence that endocytosis plays a central role in the production of Abeta in neurons.Entities:
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Year: 2009 PMID： 19491039 DOI： 10.1016/j.arr.2009.03.002
Source DB: PubMed Journal: Ageing Res Rev ISSN： 1568-1637 Impact factor: 10.895