Literature DB >> 1948997

Reduced midbrain and pons size in children with autism.

T Hashimoto1, M Tayama, M Miyazaki, K Murakawa, N Sakurama, T Yoshimoto, Y Kuroda.   

Abstract

Recent reports suggested functional abnormalities of the brain stem in autistic children. Moreover, structural brain abnormalities have also been reported, so we analyzed magnetic resonance imaging (MRI) scan in autistic children. MRI scans for 29 autistic children were compared with 15 control MRI scans. The midbrain and pons were measured. The midbrain and pons size were found to be significantly smaller in the autistic group. This suggests that the structure of the brain stem is anatomically altered in autistic children.

Entities:  

Mesh:

Year:  1991        PMID: 1948997

Source DB:  PubMed          Journal:  Tokushima J Exp Med        ISSN: 0040-8875


  5 in total

1.  Neonatal brainstem function and 4-month arousal-modulated attention are jointly associated with autism.

Authors:  Ira L Cohen; Judith M Gardner; Bernard Z Karmel; Ha T T Phan; Phyllis Kittler; Tina Rovito Gomez; Maripaz G Gonzalez; Elizabeth M Lennon; Santosh Parab; Anthony Barone
Journal:  Autism Res       Date:  2012-11-16       Impact factor: 5.216

2.  Startle modulation studies in autism.

Authors:  E M Ornitz; S J Lane; T Sugiyama; J de Traversay
Journal:  J Autism Dev Disord       Date:  1993-12

3.  Saccadic eye movement abnormalities in autism spectrum disorder indicate dysfunctions in cerebellum and brainstem.

Authors:  Lauren M Schmitt; Edwin H Cook; John A Sweeney; Matthew W Mosconi
Journal:  Mol Autism       Date:  2014-09-16       Impact factor: 7.509

4.  Zebrafish homologs of genes within 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes.

Authors:  Alicia Blaker-Lee; Sunny Gupta; Jasmine M McCammon; Gianluca De Rienzo; Hazel Sive
Journal:  Dis Model Mech       Date:  2012-05-01       Impact factor: 5.758

Review 5.  The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders.

Authors:  Matthew W Mosconi; Zheng Wang; Lauren M Schmitt; Peter Tsai; John A Sweeney
Journal:  Front Neurosci       Date:  2015-09-01       Impact factor: 4.677

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.