OBJECTIVE: To investigate outcomes of twin gestations with advanced maternal age (AMA). STUDY DESIGN: Historical cohort of twin gestations cared for by a maternal-fetal medicine faculty practice. Outcomes of patients with AMA (70) and non-AMA (75) were compared. AMA was defined as age > or =35. Analysis including mode of delivery, gestational age at delivery and overall complications was performed. Significance was determined using the chi-square test or the Student's t-test. RESULTS: The Cesarean rate for AMA was significantly greater compared to non-AMA (80.0% vs. 54.7%; p = 0.001). The main reason for the increased rate was uterine dysfunction. The mean gestational age at delivery for AMA was significantly greater than for non-AMA (36.7 weeks vs. 35.4 weeks; p = 0.02). There were no differences in rates of other adverse outcomes including gestational hypertension, pre-eclampsia, gestational diabetes, suspected fetal growth restriction, preterm birth, low birth weight or low birth weight percentiles. This remained true when we compared the 32 women ages > or =40 years to 118 women ages <40 years. CONCLUSION: Among twin pregnancies, AMA women are not at an increased risk of adverse pregnancy outcomes, aside from an increased rate of cesarean delivery.
OBJECTIVE: To investigate outcomes of twin gestations with advanced maternal age (AMA). STUDY DESIGN: Historical cohort of twin gestations cared for by a maternal-fetal medicine faculty practice. Outcomes of patients with AMA (70) and non-AMA (75) were compared. AMA was defined as age > or =35. Analysis including mode of delivery, gestational age at delivery and overall complications was performed. Significance was determined using the chi-square test or the Student's t-test. RESULTS: The Cesarean rate for AMA was significantly greater compared to non-AMA (80.0% vs. 54.7%; p = 0.001). The main reason for the increased rate was uterine dysfunction. The mean gestational age at delivery for AMA was significantly greater than for non-AMA (36.7 weeks vs. 35.4 weeks; p = 0.02). There were no differences in rates of other adverse outcomes including gestational hypertension, pre-eclampsia, gestational diabetes, suspected fetal growth restriction, preterm birth, low birth weight or low birth weight percentiles. This remained true when we compared the 32 women ages > or =40 years to 118 women ages <40 years. CONCLUSION: Among twin pregnancies, AMA women are not at an increased risk of adverse pregnancy outcomes, aside from an increased rate of cesarean delivery.
Authors: Amelia S McLennan; Cynthia Gyamfi-Bannerman; Cande V Ananth; Jason D Wright; Zainab Siddiq; Mary E D'Alton; Alexander M Friedman Journal: Am J Obstet Gynecol Date: 2017-03-09 Impact factor: 8.661
Authors: Annu-Riikka S Rissanen; Riina M Jernman; Mika Gissler; Irmeli Nupponen; Mika E Nuutila Journal: BMC Pregnancy Childbirth Date: 2019-09-18 Impact factor: 3.007
Authors: María De la Calle; Jose L Bartha; Laura García; Marcos J Cuerva; David Ramiro-Cortijo Journal: Int J Environ Res Public Health Date: 2021-12-12 Impact factor: 3.390