Literature DB >> 19488549

Pain in patients with spinal cord injury: a review.

Marcia de Miguel1, Durval Campos Kraychete.   

Abstract

BACKGROUND AND METHODS: Chronic pain after spinal cord injury is a highly prevalent clinical condition, which is difficult to treat. Therefore, it is important to know its clinical characteristics and causes for a better diagnostic and therapeutic approach. The objective of this study was to review the literature on pain in patients with spinal cord injury and the possible association with physical (level of the injury, completeness of lesion, pain duration) and psychological (mood and quality of life) factors. CONTENTS: Original studies in the Medline database with patients older than 18 years and published over the last six years were reviewed. The clinical characteristics of pain in patients with spinal cord injury are discussed, and the works of several authors are compared.
CONCLUSIONS: Despite conceptual and methodological differences among the studies, the prevalence of pain in patients with spinal cord injury was high, varying from 64% to 82%. Neuropathic pain at the level of the injury has an early onset (days or weeks), while that below the level of the injury has a late onset (months or years). An association between pain and integrity of the lesion is not observed, and the percentage of patients who complain of severe pain varies from 21% to 39%. It was not possible to conclude which is the relationship between pain and level of spinal cord injury. However, pain can have a negative influence on mood and in the capacity to perform cognitive, social, recreational, and work-related activities.

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Year:  2009        PMID: 19488549     DOI: 10.1590/s0034-70942009000300011

Source DB:  PubMed          Journal:  Rev Bras Anestesiol        ISSN: 0034-7094            Impact factor:   0.964


  4 in total

1.  Dorsal horn neuronal sparing predicts the development of at-level mechanical allodynia following cervical spinal cord injury in mice.

Authors:  Valerie Dietz; Katelyn Knox; Sherilynne Moore; Nolan Roberts; Karla Kassandra Corona; Jennifer N Dulin
Journal:  Exp Neurol       Date:  2022-03-16       Impact factor: 5.620

2.  Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord injury.

Authors:  Jaime L Watson; Tamara J Hala; Rajarshi Putatunda; Daniel Sannie; Angelo C Lepore
Journal:  PLoS One       Date:  2014-09-30       Impact factor: 3.240

3.  Evaluation of pain and its effect on quality of life and functioning in men with spinal cord injury.

Authors:  Marzieh Hassanijirdehi; Mohammad Khak; Sohrab Afshari-Mirak; Kourosh Holakouie-Naieni; Soheil Saadat; Taher Taheri; Vafa Rahimi-Movaghar
Journal:  Korean J Pain       Date:  2015-04-01

4.  Mesenchymal Stem Cell Sheet Promotes Functional Recovery and Palliates Neuropathic Pain in a Subacute Spinal Cord Injury Model.

Authors:  Kazuyoshi Yamazaki; Masahito Kawabori; Toshitaka Seki; Soichiro Takamiya; Kotaro Konno; Masahiko Watanabe; Kiyohiro Houkin; Miki Fujimura
Journal:  Stem Cells Int       Date:  2021-07-09       Impact factor: 5.443

  4 in total

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