Literature DB >> 19487761

Clinical and laboratory assessment of dehydration severity in children with acute gastroenteritis.

Patricia C Parkin1, Colin Macarthur, Amina Khambalia, Ran D Goldman, Jeremy N Friedman.   

Abstract

OBJECTIVE: To evaluate clinical and laboratory assessment of dehydration severity in children, 1 to 36 months, with acute gastroenteritis. STUDY
DESIGN: Clinical and laboratory measures and weight change following rehydration were collected for enrolled children.
SETTING: Pediatric emergency department.
RESULTS: Likelihood ratio (LR+) and 95% confidence interval (CI): for a clinical score of 0, the LR+ was 2.2 (95% CI = 0.9-5.3); for a clinical score of 1 to 4, the LR+ was 1.3 (95% CI = 0.90-1.74); for a clinical score of 5 to 8, the LR+ was 5.2 (95% CI = 2.2-12.8); for a venous pH <7.32, the LR+ was 7.2 (95% CI = 2.4-21.9); and for serum bicarbonate <18 mmol/L, the LR+ was 11.6 (95% CI = 3.5-38.0).
CONCLUSION: Clinicians may find it useful to incorporate the Clinical Dehydration Scale and laboratory measures into clinical decision-making algorithms to assess dehydration severity in children with acute gastroenteritis.

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Year:  2009        PMID: 19487761     DOI: 10.1177/0009922809336670

Source DB:  PubMed          Journal:  Clin Pediatr (Phila)        ISSN: 0009-9228            Impact factor:   1.168


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