OBJECTIVE: To investigate the distribution of joint involvement in a cohort of patients with very recent onset arthritis and describe the disease characteristics in these patients. METHODS: A very early arthritis clinic (NOR-VEAC) was established as a multicenter study. General practitioners were asked to refer patients presenting with at least 1 swollen joint of maximum 16 weeks' duration. Clinical and laboratory markers were examined. RESULTS: We included 634 patients during the first 3 years, with mean (25th-75th percentile) arthritis duration of 30 (11-63) days. Monoarthritis was present in 243 (38.3%) patients, 216 (34.1%) had oligoarthritis, and 175 (27.6%) polyarthritis. Patients with polyarthritis were older, had longer duration of arthritis, and were more frequently anti-cyclic citrullinated peptide antibody and rheumatoid factor-positive. Patients in all 3 joint pattern groups (mono-/oligo-/polyarthritis) reported substantial effect on physical function, pain, and fatigue and had elevated levels of acute-phase reactants. Knee or ankle arthritis was most frequent in patients with mono- and oligoarthritis, whereas small joint involvement was most frequent in patients with polyarthritis. CONCLUSION: Patients with recent-onset arthritis report a substantial influence on health status. Mono- and oligoarthritis are at least as frequent as polyarthritis. Polyarthritic patients more frequently exhibit features associated with a worse outcome.
OBJECTIVE: To investigate the distribution of joint involvement in a cohort of patients with very recent onset arthritis and describe the disease characteristics in these patients. METHODS: A very early arthritis clinic (NOR-VEAC) was established as a multicenter study. General practitioners were asked to refer patients presenting with at least 1 swollen joint of maximum 16 weeks' duration. Clinical and laboratory markers were examined. RESULTS: We included 634 patients during the first 3 years, with mean (25th-75th percentile) arthritis duration of 30 (11-63) days. Monoarthritis was present in 243 (38.3%) patients, 216 (34.1%) had oligoarthritis, and 175 (27.6%) polyarthritis. Patients with polyarthritis were older, had longer duration of arthritis, and were more frequently anti-cyclic citrullinated peptide antibody and rheumatoid factor-positive. Patients in all 3 joint pattern groups (mono-/oligo-/polyarthritis) reported substantial effect on physical function, pain, and fatigue and had elevated levels of acute-phase reactants. Knee or ankle arthritis was most frequent in patients with mono- and oligoarthritis, whereas small joint involvement was most frequent in patients with polyarthritis. CONCLUSION:Patients with recent-onset arthritis report a substantial influence on health status. Mono- and oligoarthritis are at least as frequent as polyarthritis. Polyarthritic patients more frequently exhibit features associated with a worse outcome.
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Authors: S Mayer-Wagner; F Wiendl; S Schewe; M Grünke; H Schulze-Koops; P Delhey; B M Holzapfel; V Jansson; J Hausdorf Journal: Z Rheumatol Date: 2010-10 Impact factor: 1.372
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Authors: Ellen Sauar Norli; Gina Hetland Brinkmann; Tore Kristian Kvien; Olav Bjørneboe; Anne Julsrud Haugen; Halvor Nygaard; Cathrine Thunem; Elisabeth Lie; Maria Dahl Mjaavatten Journal: RMD Open Date: 2017-12-22
Authors: Lara S Chapman; Michael Backhouse; Lindsay Bearne; Lindsey Cherry; Gavin Cleary; Jasmine Davey; Rachel Ferguson; Adele Grieve; Philip Helliwell; Adam Lomax; Helen McKeeman; Alan Rawlings; Robin Rees; Robbie Rooney; Sarah Ryan; Lucy Sanders; Heidi J Siddle; Sue Varley; Louise Warburton; Jim Woodburn; Edward Roddy Journal: Rheumatology (Oxford) Date: 2022-10-06 Impact factor: 7.046